WFDC1 Protein (AA 32-220) (His tag)
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- 抗原 See all WFDC1 蛋白
- WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 32-220
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This WFDC1 protein is labelled with His tag.
- 原理
- Human PS20 Protein
- 序列
- Lys32-Gln220
- 产品特性
- Recombinant Human PS20 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Lys32-Gln220.
- 纯度
- > 95 % as determined by Tris-Bis PAGE
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product WFDC1 蛋白
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Supplied as 0.22μm filtered solution in 20 mM PB, 500 mM NaCl, 200 mM L-arginine ( pH 7.4).
- 储存条件
- -80 °C
- 储存方法
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))
- 别名
- PS20 (WFDC1 产品)
- 别名
- WFDC1 Protein, zgc:158671 Protein, PS20 Protein, 2310058A03Rik Protein, ps20 Protein, WAP four-disulfide core domain 1 Protein, WFDC1 Protein, wfdc1 Protein, Wfdc1 Protein
- 背景
- The whey acidic protein family member, WFDC1/ps20 is a permissivity factor in HIV infection. Herein we describe a contrasting role for ps20 in limiting MHV-1 infection. Intranasal MHV-1 infection produces a respiratory infection in mice. Using ps20 knockout mice we provide evidence that intranasal MHV-1 infection results in increased lung viral titers in ps20(-/-) compared to ps20(/) mice. Roles for ps20 in regulating expression of neutrophil-specific chemotactic factors, thereby potentially modulating neutrophil migration, and in modulating neutrophil susceptibility to MHV-1 infection.
- 分子量
- 22 kDa. The protein migrates to 25-30 kDa based on Tris-Bis PAGE result.
- UniProt
- Q9HC57
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