PILRA
宿主: 小鼠
宿主: HEK-293 Cells
Recombinant
> 97 % as determined by SDS-PAGE
Active
限制
仅限研究用
状态
Lyophilized
溶解方式
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
缓冲液
Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
储存条件
-20 °C,-80 °C
储存方法
-20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
有效期
12 months
抗原
PILRA
(Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA))
PILRA Protein, FDF03 Protein, AV021745 Protein, RGD1562847 Protein, paired immunoglobin like type 2 receptor alpha Protein, paired immunoglobulin-like type 2 receptor alpha Protein, paired immunoglobin-like type 2 receptor alpha Protein, PILRA Protein, LOC489841 Protein, Pilra Protein
背景
Alzheimer's disease (AD) is a neurodegenerative disease characterized by a progressive decline in cognitive performance, Mild Cognitive Impairment (MCI) is instead an objective decline in cognitive performance that does not reach pathology. Paired immunoglobulin-like type 2 receptor alpha (PILRA) is a cell surface inhibitory receptor that was recently suggested to be involved in AD pathogenesis. In particular, the arginine-to-glycine substitution in position 78 (R78, rs1859788) was shown to be protective against AD.
分子量
45.4 kDa. Due to glycosylation, the protein migrates to 70-75 kDa based on Tris-Bis PAGE result.