Supplied as 0.22μm filtered solution in 20 mM Tris, 500 mM Nacl,10 % Glycerol, 0.5 mM TCEP, 1 mM EDTA ( pH 8.0).
储存液
Other preservative
储存条件
-80 °C
储存方法
Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
有效期
12 months
抗原
PAD4 (PADI4)
(Peptidyl Arginine Deiminase, Type IV (PADI4))
PAD Protein, PAD4 Protein, PADI5 Protein, PDI4 Protein, PDI5 Protein, Pad4 Protein, Pdi4 Protein, peptidyl arginine deiminase 4 Protein, peptidyl arginine deiminase, type IV Protein, PADI4 Protein, Padi4 Protein
背景
Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has post-translational modification activity (citrullination). Padi4 is mainly expressed in myeloid cells and granulocytes.