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TNFRSF4 Protein (AA 20-211) (His-Avi Tag)

TNFRSF4 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 92 % as determined by HPLC
产品编号 ABIN7275391
发货至: 中国
  • 抗原 See all TNFRSF4 蛋白
    TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
    蛋白类型
    Recombinant
    产品特性
    AA 20-211
    宿主
    • 21
    • 14
    • 5
    • 5
    • 2
    • 2
    • 1
    小鼠
    资源
    • 33
    • 8
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    标记
    This TNFRSF4 protein is labelled with His-Avi Tag.
    原理
    Mouse OX40/TNFRSF4/CD134 Protein
    序列
    Val20-Pro211
    产品特性
    Recombinant Mouse OX40/TNFRSF4/CD134 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Val20-Pro211.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 92 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Mouse OX-40 Ligand, hFc Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Mouse OX-40, His Tag with the EC50 3.59μg/ml determined by ELISA. See testing image for detail.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
    别名
    OX40 (TNFRSF4 产品)
    别名
    TNFRSF4 Protein, ACT35 Protein, CD134 Protein, Ly-70 Protein, Ox40 Protein, TXGP1L Protein, Txgp1 Protein, OX40 Protein, TNF receptor superfamily member 4 Protein, tumor necrosis factor receptor superfamily, member 4 Protein, TNFRSF4 Protein, Tnfrsf4 Protein
    背景
    Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation, its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation.
    分子量
    24.2 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
    UniProt
    P47741
    途径
    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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