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NOTCH3 Protein (AA 40-467) (His-Avi Tag)

This Recombinant NOTCH3 protein is expressed in HEK-293 Cells.
产品编号 ABIN7275366
发货至: 中国

Quick Overview for NOTCH3 Protein (AA 40-467) (His-Avi Tag) (ABIN7275366)

抗原

See all NOTCH3 蛋白
NOTCH3 (Notch 3 (NOTCH3))

蛋白类型

Recombinant

宿主

  • 8
  • 1

资源

  • 4
  • 4
  • 1
HEK-293 Cells

纯度

> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
  • 产品特性

    AA 40-467

    标记

    This NOTCH3 protein is labelled with His-Avi Tag.

    原理

    Human Notch 3 Protein

    序列

    Ala40-Glu467

    产品特性

    Recombinant Human Notch 3 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ala40-Glu467.

    过滤

    0.22 μm filtered

    内毒素水平

    Less than 1EU per μg by the LAL method.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

    缓冲液

    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    NOTCH3 (Notch 3 (NOTCH3))

    别名

    Notch 3

    背景

    Human Notch-3 is part of the Notch family of type I transmembrane glycoproteins involved in a number of early-event developmental processes. The extracellular domain of Notch receptors interact with the extracellular domain of transmembrane ligands Jagged, Delta, and Serrate expressed on the surface of a neighboring cell. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs

    分子量

    47.7 kDa. Due to glycosylation, the protein migrates to 53-60 kDa based on Tris-Bis PAGE result.

    UniProt

    Q9UM47

    途径

    Notch Signaling
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