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NOG 蛋白

NOG 宿主: 人 宿主: CHO Cells Recombinant > 95% as determined by Tris-Bis PAGE
产品编号 ABIN7275358
发货至: 中国
  • 抗原 See all NOG 蛋白
    NOG (Noggin (NOG))
    蛋白类型
    Recombinant
    宿主
    • 10
    • 10
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    资源
    • 18
    • 8
    • 4
    • 2
    • 1
    • 1
    CHO Cells
    序列
    Gln28-Cys232
    纯度
    > 95% as determined by Tris-Bis PAGE
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product NOG 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    4 °C,-80 °C
    储存方法
    Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    NOG (Noggin (NOG))
    别名
    Noggin (NOG 产品)
    别名
    SYM1 Protein, SYNS1 Protein, nog-A Protein, nog1 Protein, noggin-1 Protein, noggin Protein, noggin Protein, noggin L homeolog Protein, noggin protein Protein, NOG Protein, Nog Protein, nog.L Protein, noggin Protein
    背景
    Noggin, NOG, SYM1, SYNS1,Noggin is an antagonist of bone morphogenetic proteins (BMP), being indispensable for certain developmental events.Noggin expression positively correlated with EGFR expression in both GC cell line models and The Cancer Genome Atlas human GC cohort. Targeting EGFR and its downstream pathways diminished cell proliferation which was promoted by Noggin. Noggin promotes the proliferation of GC cells by upregulating EGFR and enhancing a vicious circle formed by β-catenin, EGFR, ERK and Akt.
    分子量
    23.05 kDa. Due to glycosylation, the protein migrates to 30-36 kDa based on Tris-Bis PAGE result.
    UniProt
    Q13253
    途径
    Stem Cell Maintenance, Tube Formation
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