MASP2 Protein (AA 287-685) (His tag)
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- 抗原 See all MASP2 蛋白
- MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))
- 蛋白类型
- Recombinant
- 产品特性
- AA 287-685
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宿主
- 小鼠
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资源
- 大肠杆菌(E. Coli)
- 标记
- This MASP2 protein is labelled with His tag.
- 原理
- Mouse MASP2 Protein
- 序列
- Thr287-Phe685
- 产品特性
- Recombinant Mouse MASP2 Protein is expressed from E.coli with His tag at the C-Terminus.It contains Thr287-Phe685.
- 纯度
- > 95 % as determined by Tris-Bis PAGE
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product MASP2 蛋白
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Supplied as 0.22μm filtered solution in 50 mM Tris, 200 mM NaCl ( pH 9.0).
- 储存条件
- -80 °C
- 储存方法
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))
- 别名
- MASP2 (MASP2 产品)
- 别名
- MAP19 Protein, MASP-2 Protein, MASP1P1 Protein, sMAP Protein, MAp19 Protein, mannan binding lectin serine peptidase 2 Protein, mannan-binding lectin serine peptidase 2 Protein, MASP2 Protein, Masp2 Protein
- 背景
- The dysregulation of complement cascade leads to unsolicited cytokine storm, inflammation, deterioration of alveolar lining cells, culminating in acquired respiratory destructive syndrome (ARDS). Similar pathogenesis is observed with the middle east respiratory syndrome (MERS), severe acquired respiratory syndrome (SARS), and SARS-CoV-2. Activation of the lectin pathway via mannose-binding lectin associated serine protease 2 (MASP2) is witnessed under discrete viral infections including COVID-19.
- 分子量
- 46.6 kDa. Due to autocatalytic cleavage, the protein migrates to 18-20 kDa&27-30 kDa based on Tris-Bis PAGE result.
- UniProt
- Q91WP0
- 途径
- Complement System
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