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Azurocidin Protein (AA 27-250) (His tag)

This Recombinant Azurocidin protein is expressed in HEK-293 Cells.
产品编号 ABIN7274790
发货至: 中国
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Quick Overview for Azurocidin Protein (AA 27-250) (His tag) (ABIN7274790)

抗原

See all Azurocidin (AZU1) 蛋白
Azurocidin (AZU1) (Azurocidin 1 (AZU1))

蛋白类型

Recombinant

生物活性

Active

宿主

  • 8
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资源

  • 2
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HEK-293 Cells

纯度

> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
  • 产品特性

    AA 27-250

    标记

    This Azurocidin protein is labelled with His tag.

    原理

    Human Azurocidin/CAP37/AZU1/HBP Protein

    序列

    Ile27-Pro250

    产品特性

    Recombinant Human Azurocidin/CAP37/AZU1 /HBP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ile27-Pro250.

    过滤

    0.22 μm filtered

    内毒素水平

    Less than 1 EU per μg by the LAL method.

    Biological Activity Comment

    Human Azurocidin on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Human Azurocidin is greater than 95% as determined by SEC-HPLC.
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  • 限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

    缓冲液

    Lyophilized from 0.22 μm filtered solution in 20 mM PB, 500 mM NaCl ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    储存条件

    -20 °C,-80 °C

    储存方法

    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Azurocidin (AZU1) (Azurocidin 1 (AZU1))

    别名

    Azurocidin

    背景

    Heparin-binding protein (HBP), also known as cationic antimicrobial protein 37 (CAP37) and Azurocidin, is a member of the serine protease family that includes Cathepsin G, neutrophil elastase (NE), and proteinase 3 (PR3). This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin. The cytotoxic action is limited to many species of Gram-negative bacteria, this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

    分子量

    25.3 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE result.

    UniProt

    P20160
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