Azurocidin Protein (AA 27-250) (His tag)
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Quick Overview for Azurocidin Protein (AA 27-250) (His tag) (ABIN7274790)
抗原
See all Azurocidin (AZU1) 蛋白蛋白类型
生物活性
宿主
资源
纯度
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产品特性
- AA 27-250
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标记
- This Azurocidin protein is labelled with His tag.
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原理
- Human Azurocidin/CAP37/AZU1/HBP Protein
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序列
- Ile27-Pro250
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产品特性
- Recombinant Human Azurocidin/CAP37/AZU1 /HBP Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ile27-Pro250.
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过滤
- 0.22 μm filtered
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内毒素水平
- Less than 1 EU per μg by the LAL method.
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Biological Activity Comment
- Human Azurocidin on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Human Azurocidin is greater than 95% as determined by SEC-HPLC.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.
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缓冲液
- Lyophilized from 0.22 μm filtered solution in 20 mM PB, 500 mM NaCl ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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储存条件
- -20 °C,-80 °C
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储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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有效期
- 12 months
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- Azurocidin (AZU1) (Azurocidin 1 (AZU1))
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别名
- Azurocidin
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背景
- Heparin-binding protein (HBP), also known as cationic antimicrobial protein 37 (CAP37) and Azurocidin, is a member of the serine protease family that includes Cathepsin G, neutrophil elastase (NE), and proteinase 3 (PR3). This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. Binds heparin. The cytotoxic action is limited to many species of Gram-negative bacteria, this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.
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分子量
- 25.3 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE result.
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UniProt
- P20160
抗原
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