CD37 Protein (AA 113-240) (Fc Tag)
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- 抗原 See all CD37 (TSPAN26) 蛋白
- CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
- 蛋白类型
- Recombinant
- 产品特性
- AA 113-240
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This CD37 protein is labelled with Fc Tag.
- 原理
- Human CD37 Protein
- 序列
- Ala113-Asn240
- 产品特性
- Recombinant Human CD37 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Ala113-Asn240.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
- 别名
- CD37 (TSPAN26 产品)
- 别名
- Tspan26 Protein, GP52-40 Protein, TSPAN26 Protein, CD37 antigen Protein, CD37 molecule Protein, Cd37 Protein, CD37 Protein
- 背景
- CD37 is a tetraspanin expressed prominently on the surface of B cells. It is an attractive molecular target exploited in the immunotherapy of B cell-derived lymphomas and leukemia. Currently, several monoclonal antibodies targeting CD37 as well as chimeric antigen receptor-based immunotherapies are being developed and investigated in clinical trials. Given the unique role of CD37 in the biology of B cells, it seems that CD37 constitutes more than a docking point for monoclonal antibodies, and targeting this molecule may provide additional benefit to relapsed or refractory patients.
- 分子量
- 41.9 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.
- 途径
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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