ACVA Protein (AA 311-426)
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- 抗原 See all ACVA 蛋白
- ACVA (Activin A (ACVA))
- 蛋白类型
- Recombinant
- 产品特性
- AA 311-426
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宿主
- 人
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资源
- HEK-293 Cells
- 原理
- Human Activin A Protein
- 序列
- Gly311-Ser426
- 产品特性
- Recombinant Human Activin A Protein is expressed from HEK293 without tag.It contains Gly311-Ser426.
- 纯度
- > 95 % as determined by Tris-Bis PAGE
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product ACVA 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in 4 mM HCI.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in 4 mM HCI. Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- ACVA (Activin A (ACVA))
- 别名
- Activin A (ACVA 产品)
- 别名
- inhibin beta A subunit Protein, Inhba Protein
- 背景
- Activin-A, a member of the TGF-β superfamily, Extensive research over the past decades illuminated fundamental roles for activin-A in essential biologic processes, including embryonic development, stem cell maintenance and differentiation, haematopoiesis, cell proliferation and tissue fibrosis. Activin-A signals through two type I and two type II receptors which, upon ligand binding, activate their kinase activity, phosphorylate the SMAD2 and 3 intracellular signaling mediators that form a complex with SMAD4, translocate to the nucleus and activate or silence gene expression.
- 分子量
- 12.97 kDa. Due to glycosylation, the protein migrates to 14-15 kDa under reduced (R) condition, and 23-25 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.
- UniProt
- P08476
- 途径
- Hormone Transport, Peptide Hormone Metabolism
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