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ACVA Protein (AA 311-426)

ACVA 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
产品编号 ABIN7273796
发货至: 中国
  • 抗原 See all ACVA 蛋白
    ACVA (Activin A (ACVA))
    蛋白类型
    Recombinant
    产品特性
    AA 311-426
    宿主
    • 12
    • 3
    • 2
    资源
    • 5
    • 5
    • 2
    • 1
    HEK-293 Cells
    原理
    Human Activin A Protein
    序列
    Gly311-Ser426
    产品特性
    Recombinant Human Activin A Protein is expressed from HEK293 without tag.It contains Gly311-Ser426.
    纯度
    > 95 % as determined by Tris-Bis PAGE
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
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    Discover our top product ACVA 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in 4 mM HCI.
    缓冲液
    Lyophilized from 0.22μm filtered solution in 4 mM HCI. Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    ACVA (Activin A (ACVA))
    别名
    Activin A (ACVA 产品)
    别名
    inhibin beta A subunit Protein, Inhba Protein
    背景
    Activin-A, a member of the TGF-β superfamily, Extensive research over the past decades illuminated fundamental roles for activin-A in essential biologic processes, including embryonic development, stem cell maintenance and differentiation, haematopoiesis, cell proliferation and tissue fibrosis. Activin-A signals through two type I and two type II receptors which, upon ligand binding, activate their kinase activity, phosphorylate the SMAD2 and 3 intracellular signaling mediators that form a complex with SMAD4, translocate to the nucleus and activate or silence gene expression.
    分子量
    12.97 kDa. Due to glycosylation, the protein migrates to 14-15 kDa under reduced (R) condition, and 23-25 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.
    UniProt
    P08476
    途径
    Hormone Transport, Peptide Hormone Metabolism
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