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BTN3A1 Protein (Biotin)

BTN3A1 宿主: 人 宿主: 人细胞 Recombinant >90 % as determined by reducing SDS-PAGE.
产品编号 ABIN7319892
发货至: 中国
  • 抗原 See all BTN3A1 蛋白
    BTN3A1 (Butyrophilin, Subfamily 3, Member A1 (BTN3A1))
    蛋白类型
    Recombinant
    宿主
    • 11
    • 3
    资源
    • 12
    • 1
    • 1
    人细胞
    标记
    This BTN3A1 protein is labelled with Biotin.
    原理
    Recombinant Human Butyrophilin Subfamily 3 Member A1/BTN3A1 (C-Fc-Avi) Biotinylated
    序列
    Gln30-Gly254
    产品特性
    Biotinylated Recombinant Human Butyrophilin Subfamily 3 Member A1 is produced by our Mammalian expression system and the target gene encoding Gln30-Gly254 is expressed with a Fc, Avi tag at the C-terminus.
    纯度
    >90 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product BTN3A1 蛋白
  • 说明

    58-62 kDa

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    BTN3A1 (Butyrophilin, Subfamily 3, Member A1 (BTN3A1))
    别名
    BTN3A1 (BTN3A1 产品)
    别名
    BT3.1 Protein, BTF5 Protein, CD277 Protein, BTN3A1 Protein, butyrophilin subfamily 3 member A1 Protein, BTN3A1 Protein, LOC100447925 Protein
    背景

    Background: Butyrophilin Subfamily 3 Member A1 (BTN3A1/CD277) is a type I transmembrane glycoprotein member of the Ig superfamily. It is expressed on a wide variety of immune cells. Similar to BTN3A2 and BTN3A3, BTN3A1 is composed of an extracellular N-terminal IgV and a membraneproximal IgC domain followed by a transmembrane domain and a cytoplasmic tail. These Ig domains are also found in B7 family costimulatory molecules, suggesting structural and functional similarities between the two protein families. BTN3A1 acts as a critical protein for the activation of Vγ9Vδ2 T cells following detection of distressed cells. The anti-tumor responses of Vγ9Vδ2 T cells may be enhanced with agonistic anti-BTNA3 antibodies.

    Synonym: Butyrophilin subfamily 3 member A1, CD277, BTN3A1, BTF5

    分子量
    52.6 kDa
    UniProt
    O00481
    途径
    Activated T Cell Proliferation
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