BTN3A1 Protein (Biotin)
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- 抗原 See all BTN3A1 蛋白
- BTN3A1 (Butyrophilin, Subfamily 3, Member A1 (BTN3A1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This BTN3A1 protein is labelled with Biotin.
- 原理
- Recombinant Human Butyrophilin Subfamily 3 Member A1/BTN3A1 (C-Fc-Avi) Biotinylated
- 序列
- Gln30-Gly254
- 产品特性
- Biotinylated Recombinant Human Butyrophilin Subfamily 3 Member A1 is produced by our Mammalian expression system and the target gene encoding Gln30-Gly254 is expressed with a Fc, Avi tag at the C-terminus.
- 纯度
- >90 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product BTN3A1 蛋白
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- 说明
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58-62 kDa
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- BTN3A1 (Butyrophilin, Subfamily 3, Member A1 (BTN3A1))
- 别名
- BTN3A1 (BTN3A1 产品)
- 别名
- BT3.1 Protein, BTF5 Protein, CD277 Protein, BTN3A1 Protein, butyrophilin subfamily 3 member A1 Protein, BTN3A1 Protein, LOC100447925 Protein
- 背景
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Background: Butyrophilin Subfamily 3 Member A1 (BTN3A1/CD277) is a type I transmembrane glycoprotein member of the Ig superfamily. It is expressed on a wide variety of immune cells. Similar to BTN3A2 and BTN3A3, BTN3A1 is composed of an extracellular N-terminal IgV and a membraneproximal IgC domain followed by a transmembrane domain and a cytoplasmic tail. These Ig domains are also found in B7 family costimulatory molecules, suggesting structural and functional similarities between the two protein families. BTN3A1 acts as a critical protein for the activation of Vγ9Vδ2 T cells following detection of distressed cells. The anti-tumor responses of Vγ9Vδ2 T cells may be enhanced with agonistic anti-BTNA3 antibodies.
Synonym: Butyrophilin subfamily 3 member A1, CD277, BTN3A1, BTF5
- 分子量
- 52.6 kDa
- UniProt
- O00481
- 途径
- Activated T Cell Proliferation
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