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APOA1 蛋白

APOA1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318169
发货至: 中国
  • 抗原 See all APOA1 蛋白
    APOA1 (Apolipoprotein A-I (APOA1))
    蛋白类型
    Recombinant
    宿主
    • 15
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    资源
    • 22
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    大肠杆菌(E. Coli)
    原理
    Recombinant Human Apolipoprotein A-I/ApoAI Protein
    序列
    Arg19-Gln267
    产品特性
    Recombinant Human Apolipoprotein A-I is produced by our E.coli expression system and the target gene encoding Arg19-Gln267 is expressed.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product APOA1 蛋白
  • 说明

    27-29 kDa

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    APOA1 (Apolipoprotein A-I (APOA1))
    别名
    Apolipoprotein A-I (APOA1 产品)
    别名
    Alp-1 Protein, Apoa-1 Protein, Brp-14 Protein, Ltw-1 Protein, Lvtw-1 Protein, Sep-1 Protein, Sep-2 Protein, Sep2 Protein, apoA-I Protein, apoa Protein, apoa1 Protein, cb49 Protein, wu:fb33f01 Protein, zgc:103718 Protein, MGC64335 Protein, MGC89745 Protein, Apo-AI Protein, ApoA-I Protein, APOA1 Protein, LOC100136573 Protein, apoa-i Protein, ApoAI Protein, apolipoprotein A1 Protein, apolipoprotein A-I Protein, apolipoprotein A-Ia Protein, apolipoprotein A-I S homeolog Protein, apolipoprotein A4 Protein, APOA1 Protein, Apoa1 Protein, apoa1a Protein, apoa1.S Protein, apoa1 Protein, LOC100136573 Protein, apoa-i Protein, apoa4 Protein
    背景

    Background: Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL) in plasma. APOA1 plays a critical role in various biological processes, such as Cholesterol metabolism, Lipid metabolism and transport, Steroid metabolism. APOA1 promotes cholesterol efflux from tissues to the liver and thus helps to clear cholesterol from arteries. Defects in this gene resulted in HDL deficiencies, including Tangier disease (TGD), systemic non-neuropathic amyloidosis, premature coronary artery disease, hepatosplenomegaly and progressive muscle wasting and weakness. In addition, ApoA-I is implicated in the anti-endotoxin function of HDL via interaction with lipopolysaccharide or endotoxin.

    Synonym: Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1, APOA1

    分子量
    29.0 kDa
    UniProt
    P02647
    途径
    Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism
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