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- 抗原 See all C5 蛋白
- C5 (Complement Component 5 (C5))
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- 大肠杆菌（E. Coli）
- 原理
- Recombinant Mouse Complement Component C5/C5 Protein
- 序列
- Asn679-Arg755
- 产品特性
- Recombinant Mouse Complement Component C5 is produced by our E.coli expression system and the target gene encoding Asn679-Arg755 is expressed.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product C5 蛋白
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Complement Component 5 (C5) (AA 19-1676) protein (His tag)
C5 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Complement Component 5 (C5) (AA 1550-1661) protein (GST tag)C5 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Complement Component 5 (C5) (AA 24-1688) (Active) protein (His tag)C5 宿主: 大鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Complement Component 5 (C5) (AA 19-1676) (Active) protein (His tag)C5 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Complement Component 5 (C5) (AA 19-1680) (Active) protein (His tag)C5 宿主: 小鼠 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Complement Component 5 (C5) (AA 19-1676) (Active) protein (His tag)C5 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Complement Component 5 (C5) (AA 19-1678) protein (His tag)C5 宿主: 兔 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
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- 说明
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12 kDa
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 350 mM NaCl, pH 7.5.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- C5 (Complement Component 5 (C5))
- 别名
- Complement Component C5 (C5 产品)
- 别名
- C5 Protein, LOC565774 Protein, C5a Protein, C5b Protein, CPAMD4 Protein, Hc Protein, RGD1561905 Protein, He Protein, complement C5 Protein, complement component 5 Protein, hemolytic complement Protein, C5 Protein, c5 Protein, Hc Protein
- 背景
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Background: Mouse Complement C5 (C5a) is a glycoprotein that belongs to a family of structurally and functionally related proteins known as anaphylatoxins. C5a is a 77 amino acid peptide that is created by the C5a convertase proteolytic cleavage of C5 αchain in the classical and alternative complement pathway (C4b2a3b, C3bBb3b). Mouse C5a has fourαhelices, plus three intra-chain disulfide bonds that form a triple loop structure. C5a functions via G-protein coupled receptor (GPCR) (C5aR/CD88). C5a is a potent chemoattractant and anaphylatoxin that acts on all classes of leukocytes and on many other cell types including endothelial, smooth muscle, kidney, liver, and neural cells. It mediates IL-8 release from bronchial epithelial cells. It also triggers an oxidative burst in macrophages and neutrophils, causing release of histamine in basophils and mast cells. C5a anaphylatoxin activity on hepatocytes results indirectly from interaction with nonparenchymal cell via prostanoid secretion. Mouse C5a shares 60 % and 82 % sequence identity to human and rat C5a, respectively.
Synonym: Complement C5, Hemolytic Complement, C5, Hc
- 分子量
- 9.0 kDa
- UniProt
- P06684
- 途径
- Complement System, Carbohydrate Homeostasis
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