VNN1 Protein (His tag)
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- 抗原 See all VNN1 蛋白
- VNN1 (Vanin 1 (VNN1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This VNN1 protein is labelled with His tag.
- 原理
- Recombinant Human VNN1/Vanin-1 Protein (His Tag)
- 序列
- Gln22-Ser490
- 产品特性
- Recombinant Human Vascular Non-Inflammatory Molecule 1 is produced by our Mammalian expression system and the target gene encoding Gln22-Ser490 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product VNN1 蛋白
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Vanin 1 (VNN1) (AA 1-513) protein (GST tag)
VNN1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Vanin 1 (VNN1) (AA 298-397) protein (GST tag)VNN1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Vanin 1 (VNN1) protein (Fc Tag)VNN1 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 96 % as determined by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- VNN1 (Vanin 1 (VNN1))
- 别名
- VNN1/Vanin-1 (VNN1 产品)
- 背景
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Background: Vanin-1 is a cell membrane protein which contains one CN hydrolase domain and belongs to the CN hydrolase family and BTD/VNN subfamily. Vanin-1 is also a member of the Vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. Vanin-1 is widely expressed with higher expression in spleen, kidney and blood and overexpressed in lesional psoriatic skin. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. Vanin-1 is an epithelial pantetheinase that provides cysteamine to tissue and regulates response to stress. Vanin-1 is expressed by enterocytes, and its absence limits intestinal epithelial cell production of proinflammatory signals. Vanin-1 regulates late adhesion steps of thymus homing under physiological, noninflammatory conditions. The early impact of vanin-1 deficiency on tumor induction was directly correlated to the amount of inflammation and subsequent epithelial proliferation rather than cell death rate. Vanin-1 Molecule was shown to be involved in the control of thymus reconstitution following sub-lethal irradiation.
Synonym: Pantetheinase, Pantetheine Hydrolase, Tiff66, Vascular Non-Inflammatory Molecule 1, Vanin-1, VNN1
- 分子量
- 53.3 kDa
- UniProt
- O95497
- 途径
- Negative Regulation of intrinsic apoptotic Signaling
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