Ube2t Protein (His tag)
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- 抗原 See all Ube2t 蛋白
- Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This Ube2t protein is labelled with His tag.
- 原理
- Recombinant Human UBE2T Protein (His Tag)
- 序列
- Met 1-Val197
- 产品特性
- A DNA sequence encoding the human UBE2T (Q9NPD8) (Met1-Val197) was fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product Ube2t 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, 30 % glycerol, 0.1 % Tween 20, 0.4 mM Chaps, pH 7.5
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))
- 别名
- UBE2T (Ube2t 产品)
- 别名
- PIG50 Protein, UBE2T Protein, 2700084L22Rik Protein, C80607 Protein, RGD1310816 Protein, hspc150 Protein, wu:fj86h11 Protein, zgc:153687 Protein, ubiquitin conjugating enzyme E2 T Protein, ubiquitin-conjugating enzyme E2T Protein, ubiquitin conjugating enzyme E2T S homeolog Protein, ubiquitin-conjugating enzyme E2T (putative) Protein, UBE2T Protein, Ube2t Protein, ube2t.S Protein, ube2t Protein
- 背景
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Background: Ube2T is the E2 ubiquitin-conjugating enzyme of the Fanconi anemia DNA repair pathway and it is overexpressed in several cancers, representing an attractive target for the development of inhibitors. Notably, UBE2T locates at 1q32.1, and the gain of 1q is frequently observed in a variety of cancers. For instance, UBE2T serves an important role in the growth of bladder cancer cells, and may be considered as a potential biomarker and therapeutic target for bladder cancer.
Synonym: Ubiquitin-Conjugating Enzyme E2 T, Cell Proliferation-Inducing Gene 50 Protein, Ubiquitin Carrier Protein T, Ubiquitin-Protein Ligase T, UBE2T
- 分子量
- 23.9 kDa
- UniProt
- Q9NPD8
- 途径
- Chromatin Binding
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