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UBE2G1 蛋白

Ube2g1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 85 % as determined by reducing SDS-PAGE.
产品编号 ABIN7198583
发货至: 中国
  • 抗原 See all UBE2G1 (Ube2g1) 蛋白
    UBE2G1 (Ube2g1) (Ubiquitin-Conjugating Enzyme E2G 1 (Ube2g1))
    蛋白类型
    Recombinant
    宿主
    • 4
    • 1
    资源
    • 1
    • 1
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    原理
    Recombinant Human UBE2G1 Protein
    序列
    Met 1-Glu 170
    产品特性
    A DNA sequence encoding the human UBE2G1 (P62253) (Met 1-Glu 170) was expressed and purified, with additional two amino acids (Gly & Pro) at the N-terminus.
    纯度
    > 85 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product Ube2g1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, 10 % glycerol, pH 7.5
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    UBE2G1 (Ube2g1) (Ubiquitin-Conjugating Enzyme E2G 1 (Ube2g1))
    别名
    UBE2G1 (Ube2g1 产品)
    背景

    Background: UBE2G1 is a member of the ubiquitin-conjugating E2 family whose members perform the second step in the ubiquitination reaction. Initially identified as the main process for protein degradation, ubiquitination is believed nowadays to be crucial for a wider range of cellular processes. The outcome of the ubiquitin-conjugation reaction, and thereby the fate of the substrate, is heavily dependent on the number of ubiquitin molecules attached and how these ubiquitin molecules are inter-connected. To deal with this complexity and to allow adequate ubiquitination in time and space, a highly sophisticated conjugation machinery has been developed. In a sequential manner, ubiquitin becomes activated by an ubiquitin-activating enzyme (E1), which then transfers the ubiquitin to a group of ubiquitin-conjugating enzymes (E2s). Next, ubiquitin-loaded E2s are interacting with ubiquitin protein ligases (E3s) and ubiquitin is conjugated to substrates on recruitment by the E3. These three key enzymes are operating in a hierarchical system, wherein two E1s and 35 E2s have been found and hundreds of E3s have been identified in humans. 

    Synonym: E217K;UBC7;UBE2G

    分子量
    19.5 kDa
    UniProt
    P62253
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