USP46 蛋白
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- 抗原 See all USP46 蛋白
- USP46 (Ubiquitin Specific Peptidase 46 (USP46))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 原理
- Recombinant Human/Mouse USP46 Protein
- 序列
- Met 1-Glu366
- 产品特性
- A DNA sequence encoding the human USP46 [(Identical to the mouse USP46 (NP_808229.1)] (Met1-Glu366) was fused with the SUMO tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product USP46 蛋白
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Ubiquitin Specific Peptidase 46 (USP46) (AA 1-366) protein (His tag)
USP46 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Ubiquitin Specific Peptidase 46 (USP46) (AA 1-366) protein (GST tag)USP46 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Ubiquitin Specific Peptidase 46 (USP46) (AA 257-365) protein (GST tag)USP46 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AA, AP
Ubiquitin Specific Peptidase 46 (USP46) protein (GST tag,His tag)USP46 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 10 % glycerol
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- USP46 (Ubiquitin Specific Peptidase 46 (USP46))
- 别名
- / USP46 (USP46 产品)
- 别名
- RGD1564808 Protein, usp46 Protein, MGC53480 Protein, 1190009E20Rik Protein, 2410018I08Rik Protein, AI451644 Protein, si:ch73-16a12.1 Protein, ubiquitin specific peptidase 46 Protein, ubiquitin specific peptidase 46 S homeolog Protein, Usp46 Protein, usp46.S Protein, USP46 Protein, usp46 Protein
- 背景
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Background: USP46 belongs to the peptidase C19 family, USP12/USP46 subfamily. Deubiquitinating enzymes (DUBs) are a large group of proteases which are also commonly referred to as deubiquitinating peptidases, deubiquitinating isopeptidases, deubiquitinases, ubiquitin proteases, ubiquitin hydrolyases, ubiquitin isopeptidases, or Dubs. They regulate ubiquitin-dependent metabolic pathways by cleaving ubiquitin-protein bonds. They also may act as negative and positive regulators of the ubiquitin system. Besides ubiquitin recycling, they are also involved in processing of ubiquitin precursors, in proofreading of protein ubiquitination and in disassembly of inhibitory ubiquitin chains. USP46 is a deubiquitinating enzyme that plays a role in behavior, possibly by regulating GABA action. It may act by mediating the deubiquitination of GAD1/GAD67. USP46 has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity and it is not involved in deubiquitination of monoubiquitinated FANCD2.
Synonym: USP46
- 分子量
- 42.4 kDa
- NCBI登录号
- NP_808229
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