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TPBG Protein (mFc Tag)

TPBG 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7319827
发货至: 中国
  • 抗原 See all TPBG 蛋白
    TPBG (Trophoblast Glycoprotein (TPBG))
    蛋白类型
    Recombinant
    宿主
    • 13
    • 3
    • 3
    • 2
    • 1
    资源
    • 14
    • 2
    • 2
    • 2
    • 1
    人细胞
    标记
    This TPBG protein is labelled with mFc Tag.
    原理
    Recombinant Human TPBG/5T4 (C-mFc)
    序列
    Ser32-Ser355
    产品特性
    Recombinant Human Trophoblast glycoprotein is produced by our Mammalian expression system and the target gene encoding Ser32-Ser355 is expressed with a mFc tag at the C-terminus.
    纯度
    >95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product TPBG 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    TPBG (Trophoblast Glycoprotein (TPBG))
    别名
    TPBG/5T4 (TPBG 产品)
    别名
    5T4 Protein, 5T4AG Protein, M6P1 Protein, AW495680 Protein, TPBG Protein, tpbg Protein, trophoblast glycoprotein Protein, trophoblast glycoprotein b Protein, TPBG Protein, Tpbg Protein, tpbgb Protein, tpbg Protein
    背景

    Background: Trophoblast glycoprotein, also known as TPBG and 5T4, it belongs to the LRR family of proteins. The C-terminus of LRR N-terminal cap (LRRNT) and LRR 1 are essential for the inhibition of the Wnt signaling pathway. TPBG may function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. It expressed by all types of trophoblasts as early as 9 weeks of development. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.

    Synonym: 5T4 , 5T4AG, M6P1, WAIF1

    分子量
    61.7 kDa
    UniProt
    Q13641
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