TLK2 蛋白
-
- 抗原 See all TLK2 蛋白
- TLK2 (Tousled-Like Kinase 2 (TLK2))
- 蛋白类型
- Recombinant
-
宿主
- 人
-
资源
- Baculovirus infected Insect Cells
- 原理
- Recombinant Human TLK2/PKU-ALPHA Protein
- 序列
- Leu 397-Asn772
- 产品特性
- A DNA sequence encoding the human TLK2 (Q86UE8-1) (Leu397-Asn772) was fused with two additional amino acids (Gly & Pro) at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product TLK2 蛋白
-
Tousled-Like Kinase 2 (TLK2) (AA 1-126) protein (GST tag)
TLK2 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Tousled-Like Kinase 2 (TLK2) protein (GST tag,His tag)TLK2 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Tousled-Like Kinase 2 (TLK2) (Transcript Variant A) protein (Myc-DYKDDDDK Tag)TLK2 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
-
- 限制
- 仅限研究用
-
- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as sterile 20 mM Tris, 500 mM NaCl, 3 mM DTT, 10 % glycerol, pH 8.0
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
- 抗原
- TLK2 (Tousled-Like Kinase 2 (TLK2))
- 别名
- TLK2/PKU-ALPHA (TLK2 产品)
- 别名
- tlk2 Protein, MGC149057 Protein, HsHPK Protein, PKU-ALPHA Protein, wu:fi16h09 Protein, wu:fi30g12 Protein, zgc:136697 Protein, 4933403M19Rik Protein, PKUalpha Protein, Tlk Protein, tousled like kinase 2 Protein, tousled-like kinase 2 Protein, tousled-like kinase 2 (Arabidopsis) Protein, tlk2 Protein, TLK2 Protein, Tlk2 Protein
- 背景
-
Background: Serine / threonine-protein kinase tousled-like 2; also known as PKU-alpha; Tousled-like kinase 2 and TLK2; is a nucleus protein which belongs to the protein kinase superfamily and Ser/Thr protein kinase family. The tousled-like kinases are an evolutionarily conserved family of proteins implicated in DNA repair; DNA replication and mitosis in metazoans and plants. Their absence from the yeasts and other eukaryotic 'microbes' suggests a specific role for them in the development of multicellular organisms. Tousled-like kinase 2 / TLK2 is widely expressed. It is present in fetal placenta; liver; kidney; pancreas; heart and skeletal muscle. It is also found in adult cell lines. Tousled-like kinase 2 / TLK2 contains one protein kinase domain. Tousled-like kinase 2 / TLK2 is rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly.
Synonym: HsHPK;PKU-ALPHA
- 分子量
- 43.6 kDa
-
