电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

TIMP1 蛋白

TIMP1 宿主: 小鼠 宿主: 人细胞 Recombinant > 95 % as determined by SDS-PAGE
产品编号 ABIN7320662
发货至: 中国
  • 抗原 See all TIMP1 蛋白
    TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
    蛋白类型
    Recombinant
    宿主
    • 11
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    小鼠
    资源
    • 18
    • 8
    • 8
    • 2
    • 1
    • 1
    • 1
    人细胞
    原理
    Recombinant Mouse TIMP1/TIMP Protein
    序列
    Cys25-Arg205
    产品特性
    Recombinant Mouse Tissue Inhibitors of Metalloproteinases 1 is produced by our Mammalian expression system and the target gene encoding Cys25-Arg205 is expressed.
    纯度
    > 95 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product TIMP1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
    别名
    TIMP1/TIMP (TIMP1 产品)
    别名
    TIMP-1 Protein, TIMP1 Protein, DKFZp468A0912 Protein, CLGI Protein, EPA Protein, EPO Protein, HCI Protein, TIMP Protein, Timp Protein, Clgi Protein, TIMP metallopeptidase inhibitor 1 Protein, tissue inhibitor of metalloproteinase 1 Protein, TIMP1 Protein, Timp1 Protein
    背景

    Background: Mouse Tissue Inhibitor of Metalloproteinases 1 (TIMP-1) is a member of TIMP family. The homologous proteins of TIMPs regulate the activity of matrix metalloproteinases (MMPs), including inhibition of active MMPs, proMMP activation, cell growth promotion, matrix binding, inhibition of angiogenesis and the induction of apoptosis. Timp-1 complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. It also mediates erythropoiesis in vitro, but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. It is known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13, and MMP-16, without MMP-14.

    Synonym: Metalloproteinase Inhibitor 1, Erythroid-Potentiating Activity, EPA, Fibroblast collagenase Inhibitor, Collagenase Inhibitor, Tissue Inhibitor of Metalloproteinases 1, TIMP-1, TIMP1, CLGI, TIMP

    分子量
    20.2 kDa
    UniProt
    P12032
You are here:
客服