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Thrombopoietin Protein (THPO) (His tag)

THPO 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE. Active
产品编号 ABIN7319081
发货至: 中国
  • 抗原 See all Thrombopoietin (THPO) 蛋白
    Thrombopoietin (THPO)
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 10
    • 10
    • 4
    • 3
    • 2
    • 2
    • 2
    资源
    • 23
    • 2
    • 2
    • 2
    • 1
    • 1
    人细胞
    标记
    This Thrombopoietin protein is labelled with His tag.
    原理
    Recombinant Human Thrombopoietin/TPO Protein (His Tag)(Active)
    序列
    Ser22-Gly353
    产品特性
    Recombinant Human Thrombopoietin is produced by our Mammalian expression system and the target gene encoding Ser22-Gly353 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Measured in a cell proliferation assay using MO7E human megakaryocytic leukemic cells. The ED50 for this effect is 0.55 ng/ml.
    Top Product
    Discover our top product THPO 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    Thrombopoietin (THPO)
    别名
    Thrombopoietin/TPO (THPO 产品)
    别名
    MGDF Protein, MKCSF Protein, ML Protein, MPLLG Protein, THCYT1 Protein, TPO Protein, Mgdf Protein, Ml Protein, Mpllg Protein, Tpo Protein, Tpo1 Protein, Tpo2 Protein, Tpo3 Protein, Tpo4 Protein, tpo Protein, LOC100231762 Protein, thrombopoietin Protein, THPO Protein, Thpo Protein, thpo Protein
    背景

    Background: Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. Lineage-specific cytokine affects the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.

    Synonym: Thrombopoietin,C-mpl ligand,Megakaryocyte colony-stimulating factor,Megakaryocyte growth and development factor,Myeloproliferative leukemia virus oncogene ligand,THPO

    分子量
    37.3 kDa
    UniProt
    P40225
    途径
    JAK/STAT Signaling, Hormone Activity
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