TXNL4B Protein (His tag)
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- 抗原 See all TXNL4B 蛋白
- TXNL4B (Thioredoxin-Like 4B (TXNL4B))
- 蛋白类型
- Recombinant
- 宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This TXNL4B protein is labelled with His tag.
- 原理
- Recombinant Human Dim2/TXNL4B Protein (His Tag)
- 序列
- Met 1-Ile 149
- 产品特性
- A DNA sequence encoding the human TXNL4B (Q9NX01) (Met 1-Ile 149) was expressed, with a polyhistide tag at the N-terminus.
- 纯度
- > 92 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product TXNL4B 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, 20 % glycerol, 0.1 % Tween20, 50 mM Arg, pH 7.5
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- TXNL4B (Thioredoxin-Like 4B (TXNL4B))
- 别名
- Dim2/TXNL4B (TXNL4B 产品)
- 别名
- RGD1305127 Protein, MGC135274 Protein, MGC84953 Protein, DLP Protein, Dim2 Protein, AI595343 Protein, D530025J19Rik Protein, thioredoxin-like 4B Protein, thioredoxin like 4B Protein, thioredoxin like 4B S homeolog Protein, Txnl4b Protein, TXNL4B Protein, txnl4b Protein, txnl4b.S Protein
- 背景
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Background: Dim2, also known as TXNL4B, is a member of the DIM1 family. The Dim protein family is composed of two classes, Dim1and Dim2, which share a common thioredoxin-like fold. They were originally identified for their role in cell cycle progression and have been found to interact with Prp6, an essential component of the spliceosome, which forms the bridge of U4/U6.U5-tri-snRNP. In spite of their biological and structural similarities, Dim1 and Dim2 proteins differ in many aspects. Dim1 bears distinctive structural motifs responsible for its interaction with other spliceosome components. Dim2 forms homodimers and contains specific domains required for its interactions with partners. This originality suggests that although both proteins are involved in pre-mRNA splicing, they are likely to be involved in different biological pathways. Dim2 roduced in E.Coli is a single, non-glycosylated polypeptide chain containing 185 amino acids and having a molecular mass of 21.1kDa. It is fused to a 36 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Dim2 has a vital role in pro-mRNA splicing. Dim2 is required in cell cycle progression for S/G2 transition and interacts with PRPF6 subunit of the spliceosome.
Synonym: Dim2;DLP
- 分子量
- 19 kDa
- UniProt
- Q9NX01
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