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Stanniocalcin 1 Protein (STC1) (His tag)

STC1 宿主: 人 宿主: 人细胞 Recombinant >95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7319806
发货至: 中国
  • 抗原 See all Stanniocalcin 1 (STC1) 蛋白
    Stanniocalcin 1 (STC1)
    蛋白类型
    Recombinant
    宿主
    • 6
    • 3
    • 3
    • 1
    资源
    • 8
    • 2
    • 1
    • 1
    人细胞
    标记
    This Stanniocalcin 1 protein is labelled with His tag.
    原理
    Recombinant Human Stanniocalcin 1/STC-1 (C-6His)
    序列
    Thr18-Ala247
    产品特性
    Recombinant Human Stanniocalcin 1 is produced by our Mammalian expression system and the target gene encoding Thr18-Ala247 is expressed with a 6His tag at the C-terminus.
    纯度
    >95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product STC1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    Stanniocalcin 1 (STC1)
    别名
    Stanniocalcin 1/STC-1 (STC1 产品)
    别名
    STC Protein, Stc Protein, stc1 Protein, MGC82280 Protein, STC1 Protein, zgc:153307 Protein, LOC777959 Protein, stanniocalcin 1 Protein, stanniocalcin 1 L homeolog Protein, stanniocalcin 1 S homeolog Protein, STC1 Protein, Stc1 Protein, stc1.L Protein, stc1.S Protein, stc1 Protein, LOC777959 Protein
    背景

    Background: Stanniocalcin 1 (STC-1) is a homodimeric glycoprotein hormone that is involved in calcium and phosphate homeostasis. It was originally identified in bony fishes, where elevation of calcium in serum causes the release of STC from the endocrine glands called the corpuscles of Stannius. STC-1 inhibits the breakdown of PAPP-A, protects cancer cells from apoptosis, reduces tumor size of liver cancers, promotes osteoblast differentiation and inhibits longitudinal bone growth directly at the growth plate. It is also a biomarker of brain and lung cancer progression. STC1 signals through inhibitory G-protein modulates CGRP receptor spatial localization during osteoblastogenesis and may function as a regulatory factor interacting with calcitonin peptide members during bone formation.

    Synonym: Stanniocalcin 1, stanniocalcin-1, STC1, STC-1, STCSTC-1

    分子量
    26.9 kDa
    UniProt
    P52823
    途径
    Hormone Activity
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