SPOCK1 Protein (AA 21-429) (His tag)
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- 抗原 See all SPOCK1 蛋白
- SPOCK1 (Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 1 (SPOCK1))
- 蛋白类型
- Recombinant
- 产品特性
- AA 21-429
- 宿主
- 人
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资源
- Baculovirus infected Insect Cells
- 标记
- This SPOCK1 protein is labelled with His tag.
- 原理
- Recombinant Human SPOCK1/Testican 1 Protein (aa 21-429, His Tag)
- 序列
- Met 1-Trp439
- 产品特性
- A DNA sequence encoding the human SPOCK1 (Q08629) ( Met 1-Trp439) was expressed with a C-terminal polyhistidine tag.
- 纯度
- > 85 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SPOCK1 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- SPOCK1 (Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 1 (SPOCK1))
- 别名
- SPOCK1/Testican 1 (SPOCK1 产品)
- 别名
- SPOCK Protein, TESTICAN Protein, TIC1 Protein, Spock Protein, Ticn1 Protein, testican Protein, SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1 Protein, sparc/osteonectin, cwcv and kazal like domains proteoglycan 1 Protein, sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1 Protein, SPOCK1 Protein, Spock1 Protein
- 背景
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Background: Osteonectin, also known as SPOCK1, is an extracellular heparan/chondroitin sulfate proteoglycan. Members of this family are known as testicans, also called SPOCKs. They are characterized structurally by an N-terminal testican-specific domain, a follistatin-like region, a calcium-binding domain, a thyroglobulin-like domain, and an acidic C-terminal domain with two putative glycosaminoglycan attachment sites. SPOCKs are enriched in brain and have been shown to regulate neuronal attachment and outgrowth. They contain inhibitory regions in several domains targeted to different classes of protease, and in some cases may act as protease inhibitors. Osteonectin contains 1 Kazal-like domain and 1 thyroglobulin type-1 domain. Up to now, little is known about osteonectin's function. It may play a role in cell-cell and cell-matrix interactions. Osteonectin also may contribute to various neuronal mechanisms in the central nervous system.
Synonym: SPOCK,TESTICAN,TIC1
- 分子量
- 48.4 kDa
- UniProt
- Q08629
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