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SMAD5 蛋白

SMAD5 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 90 % as determined by SDS-PAGE
产品编号 ABIN7320167
发货至: 中国
  • 抗原 See all SMAD5 蛋白
    SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))
    蛋白类型
    Recombinant
    宿主
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠
    资源
    • 4
    • 3
    • 2
    • 1
    Baculovirus infected Insect Cells
    原理
    Recombinant Mouse Smad5 Protein
    序列
    Thr2-Ser465
    产品特性
    A DNA sequence encoding the mouse SMAD5 (P97454) (Thr2-Ser465) was expressed and purified with two additional amino acids (Gly & Pro ) at the N-terminus.
    纯度
    > 90 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product SMAD5 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile 20 mM Tris, 500 mM Nacl,10 % glycerol, pH 8.0
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))
    别名
    Smad5 (SMAD5 产品)
    别名
    DWFC Protein, JV5-1 Protein, MADH5 Protein, Madh5 Protein, SBN Protein, fb67b04 Protein, mad Protein, madh5 Protein, sb:cb400 Protein, smd5 Protein, wu:fb67b04 Protein, SMAD5 Protein, DKFZp468M0619 Protein, 1110051M15Rik Protein, AI451355 Protein, Dwf-C Protein, MusMLP Protein, SMAD family member 5 Protein, SMAD5 Protein, Smad5 Protein, smad5 Protein
    背景

    Background: SMAD5 is a member of the SMAD family. Members of this family mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD5 is involved in the TGF-beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. It is also involved in cell signalling and modulates signals of bone morphogenetic proteins (BMP's). The binding of ligands causes the oligomerization and phosphorylation of the SMAD5 protein. SMAD5 is a receptor regulated SMAD (R-SMAD) and is activated by bone morphogenetic protein type 1 receptor kinase.

    Synonym: 1110051M15Rik,AI451355,Dwf-C,Madh5,MusMLP

    分子量
    52.2 kDa
    UniProt
    P97454
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