SMAD5 蛋白
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- 抗原 See all SMAD5 蛋白
- SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- Baculovirus infected Insect Cells
- 原理
- Recombinant Mouse Smad5 Protein
- 序列
- Thr2-Ser465
- 产品特性
- A DNA sequence encoding the mouse SMAD5 (P97454) (Thr2-Ser465) was expressed and purified with two additional amino acids (Gly & Pro ) at the N-terminus.
- 纯度
- > 90 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product SMAD5 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 20 mM Tris, 500 mM Nacl,10 % glycerol, pH 8.0
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))
- 别名
- Smad5 (SMAD5 产品)
- 别名
- DWFC Protein, JV5-1 Protein, MADH5 Protein, Madh5 Protein, SBN Protein, fb67b04 Protein, mad Protein, madh5 Protein, sb:cb400 Protein, smd5 Protein, wu:fb67b04 Protein, SMAD5 Protein, DKFZp468M0619 Protein, 1110051M15Rik Protein, AI451355 Protein, Dwf-C Protein, MusMLP Protein, SMAD family member 5 Protein, SMAD5 Protein, Smad5 Protein, smad5 Protein
- 背景
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Background: SMAD5 is a member of the SMAD family. Members of this family mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD5 is involved in the TGF-beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. It is also involved in cell signalling and modulates signals of bone morphogenetic proteins (BMP's). The binding of ligands causes the oligomerization and phosphorylation of the SMAD5 protein. SMAD5 is a receptor regulated SMAD (R-SMAD) and is activated by bone morphogenetic protein type 1 receptor kinase.
Synonym: 1110051M15Rik,AI451355,Dwf-C,Madh5,MusMLP
- 分子量
- 52.2 kDa
- UniProt
- P97454
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