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SLAMF1 Protein (His tag)

SLAMF1 宿主: 人 宿主: HEK-293 Cells Recombinant > 97 % as determined by reducing SDS-PAGE. Active
产品编号 ABIN7317747
发货至: 中国
  • 抗原 See all SLAMF1 蛋白
    SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))
    蛋白类型
    Recombinant
    生物活性
    Active
    宿主
    • 9
    • 3
    • 2
    • 1
    资源
    • 7
    • 4
    • 2
    • 1
    HEK-293 Cells
    标记
    This SLAMF1 protein is labelled with His tag.
    原理
    Recombinant Human CD150/SLAMF1 Protein (His Tag)(Active)
    序列
    Met 1-Pro 258
    产品特性
    A DNA sequence encoding the human SLAM (NP_003028.1) precursor (Met 1-Pro 258) with a C-terminal polyhistidine tag was expressed.
    纯度
    > 97 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Biological Activity Comment
    Measured by its ability to bind biotinylated recombinant human SH2D1A in a functional ELISA.
    Top Product
    Discover our top product SLAMF1 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))
    别名
    CD150/SLAMF1 (SLAMF1 产品)
    别名
    CD150 Protein, SLAM Protein, SLAMF1 Protein, 4933415F16 Protein, AA177906 Protein, CDw150 Protein, ESTM51 Protein, IPO-3 Protein, Slam Protein, RGD1560634 Protein, signaling lymphocytic activation molecule family member 1 Protein, SLAMF1 Protein, Slamf1 Protein
    背景

    Background: CD150/signaling lymphocytic activation molecule (SLAM) is a cell surface sialylated phosphoglycoprotein and belongs to the CD2 subset of the Ig superfamily of type I transmembrane glycoproteins. The CD150 receptor is expressed on thymocytes, activated and memory T cells, B cells, platelets, natural killer T cells, and mature dendritic cells, and is also detected on tumor cells of Hodgkin's lymphoma (HL) and diffuse large B-cell lymphoma with an activated B cell phenotype. Additionally, it is the immune cell receptor for measles virus (MV). As a self-ligand, CD150 performs diverse immunologic functions including T/B-cell costimulation, induction of IFN-&gamma in Th1 T-cell clones, redirection of Th2 clones to a Th1 or Th0 phenotype, and inhibition of apoptosis in B cells. Furthermore, CD150 was shown to be the second receptor for measles virus in addition to CD46, and the distribution of SLAM on various cell lines is consistent with their susceptibility to clinical isolates of measles virus.

    Synonym: Signaling Lymphocytic Activation Molecule, CDw150, IPO-3, CD150, SLAMF1, SLAM

    分子量
    25.8 kDa
    NCBI登录号
    NP_003028
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