SEMA6A Protein (His tag)
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- 抗原 See all SEMA6A 蛋白
- SEMA6A (Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6A (SEMA6A))
- 蛋白类型
- Recombinant
- 宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This SEMA6A protein is labelled with His tag.
- 原理
- Recombinant Human Semaphorin 6A/SEMA6A Protein (His Tag)
- 序列
- Met 1-Thr 649
- 产品特性
- A DNA sequence encoding the human SEMA6A (NP_065847.1) extracellular domain (Met 1-Thr 649) was expressed, with a polyhistidine tag at the C-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product SEMA6A 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- SEMA6A (Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6A (SEMA6A))
- 别名
- Semaphorin 6A/SEMA6A (SEMA6A 产品)
- 别名
- fj46c12 Protein, wu:fj46c12 Protein, zgc:66106 Protein, SEMA6A Protein, HT018 Protein, SEMA Protein, SEMA6A1 Protein, SEMAQ Protein, VIA Protein, 9330158E07 Protein, A730020P05Rik Protein, AI851735 Protein, Sema6A-1 Protein, Semaq Protein, VIa Protein, b2b997Clo Protein, sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A Protein, semaphorin 6A Protein, sema6a Protein, SEMA6A Protein, Sema6a Protein
- 背景
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Background: Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP, a member of the regenerating gene family belonging to the calcium (C-type) dependent lectin superfamily, has been found to be involved in malignancy in several different organs including the stomach, colorectum, pancreas and prostate. It is highly expressed in the gastrointestinal tract and markedly up-regulated in colon adenocarcinoma, pancreatic cancer, gastric adenocarcinoma, and inflammatory bowel disease. Expression of the Reg4 in different cell types has been associated with regeneration, cell growth and cell survival, cell adhesion and resistance to apoptosis. REG4 protein overexpression is associated with an unfavorable response to preoperative chemoradiotherapy and may be used as a predictive biomarker clinically. REG4 may play an important role in the development and progression of colorectal cancer, as well as in intestinal morphogenesis and epithelium restitution.
Synonym: HT018,SEMA,SEMA6A1,SEMAQ,VIA
- 分子量
- 72.2 kDa
- NCBI登录号
- NP_065847
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