SARS-CoV-2 NSP3 蛋白
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- 抗原 See all SARS-CoV-2 NSP3 (NSP3) 蛋白
- SARS-CoV-2 NSP3 (NSP3) (SARS-CoV-2 Papain-Like Protease (NSP3))
- 蛋白类型
- Recombinant
- 宿主
- SARS Coronavirus-2 (SARS-CoV-2)
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资源
- 大肠杆菌（E. Coli）
- 原理
- Recombinant SARS-CoV-2 NSP3 protein
- 序列
- Glu1024-Gln1198
- 产品特性
- Recombinant SARS-CoV-2 NSP3 is produced by E.coli expression system and the target gene encoding Glu1024-Gln1198 is expressed with N-His Tag
- 纯度
- >90 % as determined by SDS-PAGE
- Biological Activity Comment
- Test in progress
- Top Product
- Discover our top product NSP3 蛋白
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SARS-CoV-2 Papain-Like Protease (NSP3) (AA 1564-1878) protein (His tag)
NSP3 宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS-PAGE. SDS
SARS-CoV-2 Papain-Like Protease (NSP3) protein (His tag)NSP3 宿主: SARS Coronavirus-2 (SARS-CoV-2) 宿主: 大肠杆菌（E. Coli） Recombinant >95 % as determined by SDS-PAGE. SDS
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- SARS-CoV-2 NSP3 (NSP3) (SARS-CoV-2 Papain-Like Protease (NSP3))
- 别名
- SARS-CoV-2 NSP3 (NSP3 产品)
- 别名
- pp1ab Protein, ORF1a polyprotein;ORF1ab polyprotein Protein, ORF1ab Protein
- 物质类
- Viral Protein
- 背景
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Background: The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses. Targeting PLpro with antiviral drugs may have an advantage in not only inhibiting viral replication but also inhibiting the dysregulation of signaling cascades in infected cells that may lead to cell death in surrounding, uninfected cells.
Synonym: nsp3,PL-PRO,Papain-like proteinase,X domain(Macro domain)
- 分子量
- 22.03kDa
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