S100A1 蛋白
-
- 抗原 See all S100A1 蛋白
- S100A1 (S100 Calcium Binding Protein A1 (S100A1))
- 蛋白类型
- Recombinant
- 生物活性
- Active
-
宿主
- 人
-
资源
- 大肠杆菌（E. Coli）
- 原理
- Recombinant Human S100A1 Protein (Active)
- 序列
- Met 1-Ser 94
- 产品特性
- A DNA sequence encoding the human S100A1 (NP_006262.1) (Met 1-Ser 94) was expressed.
- 纯度
- > 97 % as determined by reducing SDS-PAGE.
- Biological Activity Comment
- 1. Measured by its binding ability in a functional ELISA.2. Immobilized recombinant human Fc-S100B at 10 μg/mL (100 μl/well) can bind biotinylated human S100A1 with a linear range of 15.6-250 ng/mL.3. Measured by its ability to bind human His-S100B in functional ELISA.
- Top Product
- Discover our top product S100A1 蛋白
-
S100 Calcium Binding Protein A1 (S100A1) (AA 1-94) protein (His tag)
S100A1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
S100 Calcium Binding Protein A1 (S100A1) (AA 1-94) protein (His-IF2DI Tag)S100A1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
S100 Calcium Binding Protein A1 (S100A1) (AA 1-94) protein (GST tag)S100A1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- 抗原
- S100A1 (S100 Calcium Binding Protein A1 (S100A1))
- 别名
- S100A1 (S100A1 产品)
- 别名
- S100 Protein, S100-alpha Protein, S100A Protein, S100A1 Protein, DKFZp468K0511 Protein, AI266795 Protein, S100a Protein, S100 calcium binding protein A1 Protein, S100A1 Protein, S100a1 Protein, s100a1 Protein
- 背景
-
Background: S100A1 is a Ca2+binding protein of the EF-hand type that belongs to the S100 protein family. S100 proteins consisting of at least 19 members exist as dimers in the cytoplasm and/or nucleus of a wide range of cells, and are involved in the regulation of a number of cellular processes such as cell-cycle progression and cell differentiation.This protein has been shown to function in the processes including stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of PKC-mediated phosphorylation.. Phosphoglucomutase is a target protein whose activity is antagonistically regulated by S100A1, and recently, S100A1 is also identified as a potent molecular chaperone and a new member of the Hsp70/Hsp90 multichaperone complex. S100A1 displays a tissue-specific expression pattern with highest levels in myocardium and is considered to be an important regulator of cardiac contractility. Accordingly, reduced expression or mutations of S100A1 gene have been implicated in cardiomyopathies.
Synonym: S100,S100-alpha,S100A
- 分子量
- 10.5 kDa
- NCBI登录号
- NP_006262
- 途径
- Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteins
-
