PPP1R1A Protein (His tag)
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- 抗原 See all PPP1R1A 蛋白
- PPP1R1A (Protein Phosphatase Inhibitor 1 (PPP1R1A))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This PPP1R1A protein is labelled with His tag.
- 原理
- Recombinant Human PPP1R1A Protein (His Tag)
- 序列
- Met 1-Val171
- 产品特性
- Recombinant Human Protein Phosphatase 1 Regulatory Subunit 1A is produced by our E.coli expression system and the target gene encoding Met1-Val171 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PPP1R1A 蛋白
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, 1 mM DTT, 50 % Glycerol, pH 8.5.
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- PPP1R1A (Protein Phosphatase Inhibitor 1 (PPP1R1A))
- 别名
- PPP1R1A (PPP1R1A 产品)
- 别名
- I1 Protein, IPP1 Protein, 0610038N18Rik Protein, I-1 Protein, pil Protein, IPP-1 Protein, protein phosphatase 1 regulatory inhibitor subunit 1A Protein, protein phosphatase 1, regulatory (inhibitor) subunit 1A Protein, protein phosphatase 1 regulatory inhibitor subunit 1A L homeolog Protein, PPP1R1A Protein, Ppp1r1a Protein, ppp1r1a.L Protein
- 背景
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Background: Protein Phosphatase 1 Regulatory Subunit 1A (PPP1R1A) is an inhibitor of protein-phosphatase 1. PPP1R1A is a cellular regulator of eIF2 alpha phosphorylation. In hormonal control of glycogen metabolism, IPP-1 protein plays important function. Hormones can elevate intracellular cAMP level and elevate IPP-1 activity. PPP1R1A activation caused cAMP increase , cAMP control over proteins that are not directly phosphorylated by PKA following a rise in intracellular calcium. IPP-1 is inactivated by calcineurin (PP2B). Multiple domains in IPP-1 target cellular PP1 complexes.
Synonym: Protein Phosphatase 1 Regulatory Subunit 1A, Protein Phosphatase Inhibitor 1, I-1, IPP-1, PPP1R1A, IPP1
- 分子量
- 20.0 kDa
- UniProt
- Q13522
- 途径
- Cellular Glucan Metabolic Process
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