PROCR Protein (His tag)
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- 抗原 See all PROCR 蛋白
- PROCR (Protein C Receptor, Endothelial (PROCR))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This PROCR protein is labelled with His tag.
- 原理
- Recombinant Human EPCR Protein (His Tag)
- 序列
- Met 1-Thr 209
- 产品特性
- A DNA sequence encoding the extracellular domain of human PROCR (Q9UNN8) (Met 1-Thr 209), was fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 97 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product PROCR 蛋白
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Protein C Receptor, Endothelial (PROCR) (AA 1-238) protein (GST tag)
PROCR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Protein C Receptor, Endothelial (PROCR) protein (His tag)PROCR 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
Protein C Receptor, Endothelial (PROCR) protein (His tag)PROCR 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 96 % as determined by SDS-PAGE
Protein C Receptor, Endothelial (PROCR) protein (Fc Tag)PROCR 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- PROCR (Protein C Receptor, Endothelial (PROCR))
- 别名
- EPCR (PROCR 产品)
- 别名
- PROCR Protein, CCCA Protein, CCD41 Protein, EPCR Protein, AI325044 Protein, Ccca Protein, Ccd41 Protein, Epcr Protein, protein C receptor Protein, protein C receptor, endothelial Protein, PROCR Protein, Procr Protein
- 背景
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Background: Endothelial protein C receptor (EPCR); also known as activated protein C receptor (APC receptor) or PROCR; is a receptor for Protein C. Protein C plays an important role in many metabolism processes in humans and other animals after activated by binding to Endothelial protein C receptor (EPCR). Because of the EPCR is found primarily on endothelial cells (cells on the inside of blood vessels); activated protein C is found maily near endothelial cells. Protein C is pleiotropic; with two main functions: anticoagulation and cytoprotection. Which function will be performed depend on whether or not protein C remains bind to EPCR after activated. The anticoagulation occurs when it does not. In this case; protein C functions as an anticoagulant by irreversibly proteolytically inactivating Factor Va and Factor VIIIa; turning them into Factor Vi and Factor VIIIi respectively. When still bound to EPCR; activated protein C performs its cytoprotective effects; acting on the effector substrate PAR-1; protease-activated receptor-1. To a degree; APC's anticoagulant properties are independent of its cytoprotective ones; in that expression of one pathway is not affected by the existence of the other.
Synonym: Endothelial Protein C Receptor; Activated Protein C Receptor; APC Receptor; Endothelial Cell Protein C Receptor; CD201; PROCR; EPCR
- 分子量
- 23.4 kDa
- UniProt
- Q9UNN8
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