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Prosaposin Protein (PSAP) (His tag)

PSAP 宿主: 人 宿主: HEK-293 Cells Recombinant > (79.8+19.7) % as determined by reducing SDS-PAGE..
产品编号 ABIN7317152
发货至: 中国
  • 抗原 See all Prosaposin (PSAP) 蛋白
    Prosaposin (PSAP)
    蛋白类型
    Recombinant
    宿主
    • 4
    • 1
    • 1
    • 1
    • 1
    资源
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    标记
    This Prosaposin protein is labelled with His tag.
    原理
    Recombinant Human PSAP/Prosaposin Protein (His Tag)
    序列
    Met 1-Asn524
    产品特性
    A DNA sequence encoding the human PSAP (NP_002769.1) (Met1-Asn524) was expressed with a polyhistidine tag at the C-terminus.
    纯度
    > (79.8+19.7) % as determined by reducing SDS-PAGE..
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product PSAP 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    Prosaposin (PSAP)
    别名
    PSAP/Prosaposin (PSAP 产品)
    别名
    GLBA Protein, SAP1 Protein, AI037048 Protein, SGP-1 Protein, SGP1A Protein, cb759 Protein, wu:fa14a06 Protein, wu:fb36e02 Protein, wu:fb58g07 Protein, PSAP Protein, PSP-A Protein, SFTPA1B Protein, SP-A Protein, prosaposin Protein, surfactant protein A1 Protein, PSAP Protein, Psap Protein, psap Protein, LOC100011417 Protein, LOC100304726 Protein, LOC100526719 Protein, SFTPA1 Protein
    背景

    Background: This gene encodes a highly conserved preproprotein that is proteolytically processed to generate four main cleavage products including saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

    Synonym: GLBA,SAP1

    分子量
    57.9 kDa
    NCBI登录号
    NP_002769
    途径
    Positive Regulation of Endopeptidase Activity
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