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PRCP Protein (His tag)

PRCP 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318751
发货至: 中国
  • 抗原 See all PRCP 蛋白
    PRCP (Prolylcarboxypeptidase (PRCP))
    蛋白类型
    Recombinant
    宿主
    • 3
    • 2
    • 1
    • 1
    资源
    • 4
    • 1
    • 1
    • 1
    人细胞
    标记
    This PRCP protein is labelled with His tag.
    原理
    Recombinant Human PRCP Protein (His Tag)
    序列
    Leu22-His496
    产品特性
    Recombinant Human Lysosomal Pro-X Carboxypeptidase is produced by our Mammalian expression system and the target gene encoding Leu22-His496 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product PRCP 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of 20 mM NaAc-HAc,150 mM NaCl,10 % Glycerol, pH 4.5.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    PRCP (Prolylcarboxypeptidase (PRCP))
    别名
    PRCP (PRCP 产品)
    别名
    OI13 Protein, PCOLC Protein, PCP Protein, PCP2 Protein, TLD Protein, humpcp Protein, MGC145178 Protein, 2510048K03Rik Protein, 2610104A14Rik Protein, AI451719 Protein, HUMPCP Protein, zgc:91816 Protein, bone morphogenetic protein 1 Protein, prolylcarboxypeptidase Protein, lysosomal Pro-X carboxypeptidase Protein, prolylcarboxypeptidase (angiotensinase C) Protein, BMP1 Protein, prcp Protein, LOC5579822 Protein, CpipJ_CPIJ006123 Protein, CpipJ_CPIJ006124 Protein, Prcp Protein, PRCP Protein
    背景

    Background: Lysosomal Pro-X Carboxypeptidase (PRCP) belongs to the peptidase S28 family. PRCP is detected in many tissues, with highest levels observed in placenta, lung, and liver. It is also present in the heart, brain, pancreas, and kidney. PRCP exists as a homodimer. PRCP cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH , but enzymatic activity is retained with some substrates at neutral pH . PRCP has been shown to be an activator of the cell matrix-associated prekallikrein.

    Synonym: Lysosomal Pro-X Carboxypeptidase, Angiotensinase C, Lysosomal Carboxypeptidase C, Proline Carboxypeptidase, Prolylcarboxypeptidase, PRCP, PRCP, PCP

    分子量
    54.5 kDa
    UniProt
    P42785
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