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Prolactin Protein (PRL) (His tag)

PRL 宿主: 人 宿主: 人细胞 Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318933
发货至: 中国
  • 抗原 See all Prolactin (PRL) 蛋白
    Prolactin (PRL)
    蛋白类型
    Recombinant
    宿主
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    资源
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    人细胞
    标记
    This Prolactin protein is labelled with His tag.
    原理
    Recombinant Human Prolactin/PRL Protein (His Tag)
    序列
    Leu29-Cys227
    产品特性
    Recombinant Human Prolactin is produced by our Mammalian expression system and the target gene encoding Leu29-Cys227 is expressed with a 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product PRL 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    Prolactin (PRL)
    别名
    Prolactin/PRL (PRL 产品)
    别名
    PRL Protein, prolactin Protein, PRLB Protein, PRLSD1 Protein, Prl1a1 Protein, Prol Protein, RATPRLSD1 Protein, RNPROL Protein, AV290867 Protein, prl Protein, prolactin Protein, prolactin, gene 2 L homeolog Protein, PROLACTIN protein Protein, prolactin-like Protein, PRL Protein, prl.2.L Protein, Prl Protein, LOC100136792 Protein, LOC100136580 Protein, PROLACTIN Protein, LOC101843376 Protein
    背景

    Background: Prolactin (PRL) is a secreted neuroendocrine pituitary hormone that acts primarily on the mammary gland to promote lactation, but has pleiotropic effects in both males and females. Non-glycosylated prolactin is produced by the pituitary and packaged in storage granules before secretion, while glycosylated prolactin is reported to be constitutively secreted, have lower biological potency, and be removed from the circulation more quickly. Prolactin is synthesized mainly by the anterior pituitary in all mammals, where secretion is under tonic inhibition by hypothalamic dopamine. In humans, prolactin is also produced peripherally. Prolactin expression is low during early human pregnancy, but increases in late pregnancy. The prolactin receptor (PRLR) is a transmembrane type I glycoprotein that belongs to the cytokine hematopoietic receptor family. prolactin molecule is thought to bind two receptor molecules. In addition to its lactogenic activity, peripherally produced prolactin plays roles in breast and prostate cancer development, regulation of reproductive function, and immunoregulation.

    Synonym: Prolactin, PRL

    分子量
    23.9 kDa
    UniProt
    P01236
    途径
    JAK/STAT Signaling, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Protein targeting to Nucleus
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