PDGFRB Protein (His tag)
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- 抗原 See all PDGFRB 蛋白
- PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This PDGFRB protein is labelled with His tag.
- 原理
- Recombinant Human PDGFRB/CD140b Protein (His Tag)
- 序列
- Leu33-Phe530
- 产品特性
- Recombinant Human Platelet-Derived Growth Factor Receptor beta is produced by our Mammalian expression system and the target gene encoding Leu33-Phe530 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PDGFRB 蛋白
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Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 33-530) protein (His-Avi Tag)
PDGFRB 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 33-531) protein (His tag)PDGFRB 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Platelet Derived Growth Factor Receptor beta (PDGFRB) protein (His-Avi Tag,Biotin)PDGFRB 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 33-133) protein (GST tag)PDGFRB 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Platelet Derived Growth Factor Receptor beta (PDGFRB) (Active) protein (His tag)PDGFRB 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Platelet Derived Growth Factor Receptor beta (PDGFRB) (AA 33-532) protein (His tag)PDGFRB 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Platelet Derived Growth Factor Receptor beta (PDGFRB) (Active) protein (Fc Tag)PDGFRB 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
Platelet Derived Growth Factor Receptor beta (PDGFRB) (Active) protein (Myc-DYKDDDDK Tag)PDGFRB 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD, Func, PI Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
- 别名
- PDGFRB/CD140b (PDGFRB 产品)
- 别名
- AI528809 Protein, CD140b Protein, PDGFR-1 Protein, Pdgfr Protein, CD140B Protein, IBGC4 Protein, JTK12 Protein, PDGFR Protein, PDGFR1 Protein, platelet derived growth factor receptor, beta polypeptide Protein, platelet derived growth factor receptor beta Protein, Pdgfrb Protein, PDGFRB Protein
- 背景
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Background: Platelet-Derived Growth Factor Receptor β (PDGFR-β) is a member of the protein kinase superfamily and CSF-1/PDGF receptor subfamily. The PDGF family consists of PDGF-A, -B, -C and -D, which form either homo- or heterodimers (PDGF-AA, -AB, -BB, -CC, -DD). The four PDGFs are inactive in their monomeric forms. The PDGFs bind to the protein tyrosine kinase receptors PDGF receptor-α and -β. These two receptor isoforms dimerize upon binding the PDGF dimer, leading to three possible receptor combinations, namely -αα, -ββ and -αβ. The extracellular region of the PDGF receptor-β consists of five immunoglobulin-like domains while the intracellular part is a tyrosine kinase domain. In addition to being a potent mitogen for cells of mesenchymal origin, PDGF has also been shown to be a potent chemoattractant for mesenchymal cells, mononuclear cells, and neutrophils and has been reported to be important in the modification of cellular matrix constituents.
Synonym: Platelet-Derived Growth Factor Receptor Beta, PDGF-R-Beta, PDGFR-Beta, Beta Platelet-Derived Growth Factor Receptor, Beta-Type Platelet-Derived Growth Factor Receptor, CD140 Antigen-Like Family Member B, Platelet-Derived Growth Factor Receptor 1, PDGFR-1, CD140b, PDGFRB, PDGFR, PDGFR1,CD140B,IBGC4,IMF1,JTK12,KOGS,PENTT
- 分子量
- 57.2 kDa
- UniProt
- P09619
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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