PDGFRA Protein (His tag)
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- 抗原 See all PDGFRA 蛋白
- PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This PDGFRA protein is labelled with His tag.
- 原理
- Recombinant Human PDGFRa/CD140a Protein (His Tag)
- 序列
- Gln24-Glu524
- 产品特性
- Recombinant Human PDGFRa is produced by our Mammalian expression system and the target gene encoding Gln24-Glu524 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PDGFRA 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
- 别名
- PDGFRa/CD140a (PDGFRA 产品)
- 别名
- AI115593 Protein, CD140a Protein, Pdgfr-2 Protein, APDGFR Protein, PDGFACE Protein, CD140A Protein, PDGFR-2 Protein, PDGFR2 Protein, RHEPDGFRA Protein, PDGFR Protein, PDGFR-A Protein, platelet derived growth factor receptor alpha Protein, platelet derived growth factor receptor, alpha polypeptide Protein, platelet-derived growth factor receptor, alpha polypeptide L homeolog Protein, platelet-derived growth factor receptor, alpha polypeptide Protein, PDGFRA Protein, Pdgfra Protein, pdgfra.L Protein
- 背景
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Background: Platelet-derived Growth Factor Receptor Alpha (PDGF Rα) is an enzyme that belongs to the class III subfamily of receptor tyrosine kinases.It is a type I transmembrane glycoprotein, and can form homo- or hetero-dimeric receptors when engaged by dimers of the PDGF family of growth factors, PDGF Rα is strongly expressed in oligodendrocyte, lung, skin and intestinal progenitor cells and induced by inflammation or growth in culture, but is lowly expressed in most mesenchymal cells. PDGF Rα autophosphorylates upon dimerization, activating signaling cascades in PI-3kinase Ras-MAP kinase, and PLC-γ pathways. PDGF Rα has infulence on local gradients of epithelially produced PDGF-AA or PDGF-CC during formation of the cranial ,cardiac neural crest and interstitial kidney mesenchyme.
Synonym: CD140A,PDGFR-2,PDGFR2,RHEPDGFRA,Platelet-derived growth factor receptor alpha, PDGFR-alpha, Alpha platelet-derived growth factor receptor,CD140 antigen-like family member A, Platelet-derived growth factor alpha receptor, Platelet-derived growth factor receptor 2
- 分子量
- 57 kDa
- UniProt
- P16234
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
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