PLA2G12B Protein (His tag)
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- 抗原 See all PLA2G12B 蛋白
- PLA2G12B (Phospholipase A2, Group XIIB (PLA2G12B))
- 蛋白类型
- Recombinant
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宿主
- 小鼠
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资源
- HEK-293 Cells
- 标记
- This PLA2G12B protein is labelled with His tag.
- 原理
- Recombinant Mouse PLA2G12B/PLA2G13 Protein (His Tag)
- 序列
- Met 1-Leu 195
- 产品特性
- A DNA sequence encoding the mouse PLA2G12B (NP_076019.2) (Met 1-Leu 195) was expressed, with a C-terminal polyhistidine tag.
- 纯度
- > 95 % as determined by SDS-PAGE
- 内毒素水平
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product PLA2G12B 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile 20 mM NaAc, 100 mM NaCl, pH 5.0
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- PLA2G12B (Phospholipase A2, Group XIIB (PLA2G12B))
- 别名
- PLA2G12B/PLA2G13 (PLA2G12B 产品)
- 别名
- wu:fb26d02 Protein, wu:fb99g06 Protein, wu:fc91d12 Protein, zgc:111897 Protein, zgc:56487 Protein, zgc:77746 Protein, MGC79728 Protein, GXIIB Protein, GXIIIsPLA2 Protein, PLA2G13 Protein, 2010002E04Rik Protein, Pla2g13 Protein, hlb218 Protein, phospholipase A2, group XIIB Protein, phospholipase A2 group XIIB Protein, pla2g12b Protein, PLA2G12B Protein, Pla2g12b Protein
- 背景
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Background: Group XIIB secretory phospholipase A2-like protein, also known as Group XIII secretory phospholipase A2-like protein, GXIII sPLA2-like, sPLA2-GXIIB, GXIIB, PLA2G13 and PLA2G12B, is a secreted protein which belongs to the phospholipase A2 family. PLA2G12B / PLA2G13 is strong expression in liver, small intestine and kidney. Mammalian secretory phospholipase A2s ( sPLA2s ) form a family of structurally related enzymes that are involved in a variety of physiological and pathological processes via the release of arachidonic acid from membrane phospholipids or the binding to specific membrane receptors. Phospholipases A2 / PLA2 are enzymes that release fatty acids from the second carbon group of glycerol. This particular phospholipase specifically recognizes the sn-2 acyl bond of phospholipids and catalytically hydrolyzes the bond releasing arachidonic acid and lysophospholipids. Phospholipases A2 / PLA2 are commonly found in mammalian tissues as well as insect and snake venom. Venom from both snakes and insects is largely composed of melittin, which is a stimulant of Phospholipases A2 / PLA2. Due to the increased presence and activity of Phospholipases A2 / PLA2 resulting from a snake or insect bite, arachidonic acid is released from the phospholipid membrane disproportionately. As a result, inflammation and pain occur at the site.
Synonym: 2010002E04Rik;Fksg71;hlb218;Pla2g13
- 分子量
- 21 kDa
- NCBI登录号
- NP_076019
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