PDE9A Protein (His tag)
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- 抗原 See all PDE9A 蛋白
- PDE9A (phosphodiesterase 9A (PDE9A))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This PDE9A protein is labelled with His tag.
- 原理
- Recombinant Human PDE9A Protein (His Tag)
- 序列
- Pro 181-Lys 506
- 产品特性
- A DNA sequence encoding the human PDE9A (O76083-2) C-terminal segment (Pro 181-Lys 506) was expressed, with a polyhistide tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product PDE9A 蛋白
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phosphodiesterase 9A (PDE9A) (AA 434-533) protein (GST tag)
PDE9A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
phosphodiesterase 9A (PDE9A) (AA 1-533) protein (GST tag)PDE9A 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
phosphodiesterase 9A (PDE9A) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)PDE9A 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
phosphodiesterase 9A (PDE9A) (Transcript Variant 13) protein (Myc-DYKDDDDK Tag)PDE9A 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
phosphodiesterase 9A (PDE9A) (Transcript Variant 9) protein (Myc-DYKDDDDK Tag)PDE9A 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- PDE9A (phosphodiesterase 9A (PDE9A))
- 别名
- PDE9A (PDE9A 产品)
- 别名
- PDE9A Protein, MGC116558 Protein, Pde9a Protein, HSPDE9A2 Protein, PDE9A1 Protein, phosphodiesterase 9A Protein, phosphodiesterase 9A S homeolog Protein, high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A Protein, PDE9A Protein, pde9a.S Protein, Pde9a Protein, LOC100549810 Protein, pde9a Protein
- 背景
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Background: High affinity cGMP-specific 3';5'-cyclic phosphodiesterase 9A; also known as PDE9A; is a member of the cyclic nucleotide phosphodiesterase family and PDE9 subfamily. PDE9A is expressed in all tissues examined (testis; brain; small intestine; skeletal muscle; heart; lung; thymus; spleen; placenta; kidney; liver; pancreas; ovary and prostate) except blood. Highest levels of PDE9A is in brain; heart; kidney; spleen; prostate and colon. Isoform PDE9A12 is found in prostate. PDE9A mRNA is widely distributed throughout the rat and mouse brain; with the highest expression observed in cerebellar Purkinje cells. PDE9A is the only cGMP-specific PDE with significant expression in the forebrain; and as such is likely to play an important role in NO-cGMP signaling. PDE9A is highly conserved between species and is widely distributed throughout the rodent brain. PDE9A is probably involved in maintenance of low cGMP levels in cells and might play an important role in a variety of brain functions involving cGMP-mediated signal transduction. PDE9A hydrolyzes the second messenger cGMP; which is a key regulator of many important physiological processes. PDE9A represents a novel drug target worthy of further study.
Synonym: HSPDE9A2
- 分子量
- 40 kDa
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