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Peroxiredoxin 1 Protein (PRDX1) (His tag)

PRDX1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7318889
发货至: 中国
  • 抗原 See all Peroxiredoxin 1 (PRDX1) 蛋白
    Peroxiredoxin 1 (PRDX1)
    蛋白类型
    Recombinant
    宿主
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    资源
    • 8
    • 3
    • 3
    • 1
    • 1
    大肠杆菌(E. Coli)
    标记
    This Peroxiredoxin 1 protein is labelled with His tag.
    原理
    Recombinant Human Peroxiredoxin 1/PRDX1 Protein (His Tag)
    序列
    Met 1-Lys199
    产品特性
    Recombinant Human Peroxiredoxin-1 is produced by our E.coli expression system and the target gene encoding Met1-Lys199 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product PRDX1 蛋白
  • 限制
    仅限研究用
  • 状态
    Frozen, Liquid
    缓冲液
    Supplied as a 0.2 μm filtered solution of PBS, 10 % glycerol, 0.1 mM DTT, pH 6.0.
    储存条件
    -20 °C
    储存方法
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • 抗原
    Peroxiredoxin 1 (PRDX1)
    别名
    Peroxiredoxin 1/PRDX1 (PRDX1 产品)
    别名
    MSP23 Protein, NKEF-A Protein, NKEFA Protein, PAG Protein, PAGA Protein, PAGB Protein, PRX1 Protein, PRXI Protein, TDPX2 Protein, NkefA Protein, OSF-3 Protein, OSF3 Protein, Paga Protein, PrdxI Protein, PrxI Protein, TDX2 Protein, TPxA Protein, Tdpx2 Protein, prx1 Protein, Hbp23 Protein, MGC80194 Protein, MGC84820 Protein, PRDX1 Protein, msp23 Protein, nkefa Protein, pag Protein, paga Protein, pagb Protein, prx-1 Protein, prxi Protein, tdpx2 Protein, hm:zehl0637 Protein, zgc:110343 Protein, TPX-2 Protein, peroxiredoxin 1 Protein, peroxiredoxin 1 S homeolog Protein, peroxiredoxin-1 pseudogene Protein, PRDX1 Protein, Prdx1 Protein, prdx1.S Protein, prdx1 Protein, LOC100350232 Protein
    背景

    Background: Peroxiredoxin-1(PRDX1) contains 1 thioredoxin domain and belongs to the AhpC/TSA family. PRDX1 constitutively expressed in most human cells and it is induced to higher levels upon serum stimulation in untransformed and transformed cells. PRDX1 is involved in redox regulation of the cell. It reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin and play an important role in eliminating peroxides generated during metabolism. PRDX1 might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. It reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation. It may contribute to the antiviral activity of CD8(+) T-cells and have a proliferative effect in cancer development or progression.

    Synonym: Peroxiredoxin-1,Natural killer cell-enhancing factor A,NKEF-A,Proliferation-associated gene protein,PAG,Thioredoxin peroxidase 2,Thioredoxin-dependent peroxide reductase 2,PAGA, PAGB, TDPX2,MSP23,NKEF-A,NKEFA,PAG,PRX1,PRXI,TDPX2

    分子量
    25.3 kDa
    UniProt
    Q06830
    途径
    p53 Pathway, EGFR Signaling Pathway, CXCR4-mediated Signaling Events
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