Peroxiredoxin 1 Protein (PRDX1) (His tag)
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- 抗原 See all Peroxiredoxin 1 (PRDX1) 蛋白
- Peroxiredoxin 1 (PRDX1)
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This Peroxiredoxin 1 protein is labelled with His tag.
- 原理
- Recombinant Human Peroxiredoxin 1/PRDX1 Protein (His Tag)
- 序列
- Met 1-Lys199
- 产品特性
- Recombinant Human Peroxiredoxin-1 is produced by our E.coli expression system and the target gene encoding Met1-Lys199 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PRDX1 蛋白
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Peroxiredoxin 1 (PRDX1) (AA 1-199) protein (GST tag)
PRDX1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Peroxiredoxin 1 (PRDX1) protein (His tag)PRDX1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 85 % as determined by SDS-PAGE
Peroxiredoxin 1 (PRDX1) (AA 1-199), (full length) protein (GST tag)PRDX1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant 95 % ELISA
Peroxiredoxin 1 (PRDX1) (AA 1-199) (Active) protein (His tag)PRDX1 宿主: 小鼠 宿主: Baculovirus infected Insect Cells Recombinant > 90 % by SDS - PAGE SDS Active
Peroxiredoxin 1 (PRDX1) proteinPRDX1 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS, WB, ELISA, IP
Peroxiredoxin 1 (PRDX1) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)PRDX1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of PBS, 10 % glycerol, 0.1 mM DTT, pH 6.0.
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- 抗原
- Peroxiredoxin 1 (PRDX1)
- 别名
- Peroxiredoxin 1/PRDX1 (PRDX1 产品)
- 背景
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Background: Peroxiredoxin-1(PRDX1) contains 1 thioredoxin domain and belongs to the AhpC/TSA family. PRDX1 constitutively expressed in most human cells and it is induced to higher levels upon serum stimulation in untransformed and transformed cells. PRDX1 is involved in redox regulation of the cell. It reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin and play an important role in eliminating peroxides generated during metabolism. PRDX1 might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. It reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation. It may contribute to the antiviral activity of CD8(+) T-cells and have a proliferative effect in cancer development or progression.
Synonym: Peroxiredoxin-1,Natural killer cell-enhancing factor A,NKEF-A,Proliferation-associated gene protein,PAG,Thioredoxin peroxidase 2,Thioredoxin-dependent peroxide reductase 2,PAGA, PAGB, TDPX2,MSP23,NKEF-A,NKEFA,PAG,PRX1,PRXI,TDPX2
- 分子量
- 25.3 kDa
- UniProt
- Q06830
- 途径
- p53 Pathway, EGFR Signaling Pathway, CXCR4-mediated Signaling Events
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