PPIA 蛋白
-
- 抗原 See all PPIA 蛋白
- PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))
- 蛋白类型
- Recombinant
-
宿主
- 人
-
资源
- 大肠杆菌（E. Coli）
- 原理
- Recombinant Human Cyclophilin A Protein
- 序列
- Met 1-Glu165
- 产品特性
- Recombinant Human Peptidyl-prolyl Cis-trans Isomerase A is produced by our E.coli expression system and the target gene encoding Met1-Glu165 is expressed.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PPIA 蛋白
-
Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA) (AA 1-165) protein (GST tag)
PPIA 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA) proteinPPIA 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % as determined by SDS-PAGE
Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA) (AA 1-165) proteinPPIA 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % by SDS - PAGE SDS
Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA) (AA 1-164) protein (His tag)PPIA 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA) (AA 1-165) protein (His tag)PPIA 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
-
- 限制
- 仅限研究用
-
- 状态
- Frozen, Liquid
- 缓冲液
- Supplied as a 0.2 μm filtered solution of PBS, 10 % glycerol, pH 7.4 .
- 储存条件
- -20 °C
- 储存方法
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
-
- 抗原
- PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))
- 别名
- Cyclophilin A (PPIA 产品)
- 背景
-
Background: Peptidyl-prolyl cis-trans isomerase A is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family, which catalyzes the cis-trans isomerization of proline imidic peptide bonds. Cyclophilin A regulate many biological processes, including intracellular signaling, transcription, inflammation, and apoptosis. Cyclophilin is also incorporated into many viruses, including HIV1, where it has been speculated to be involved in functions such as viral assembly and infectivity. The immunosuppressive activity of cyclosporins has been correlated with their ability to form complexes with cyclophilins that inhibit calcineurin phosphatase activity and prevent incorporation of cyclophilin into viral particles. The cyclosporin/cyclophilin complex selectively binds and inactivates calcineurin, making it a useful inhibitor for studying calcineurin activity.
Synonym: Peptidyl-prolyl cis-trans isomerase A, PPIase A, Cyclophilin A, Cyclosporin A-binding protein, Rotamase A, SP18, PPIA, CYPA
- 分子量
- 18 kDa
- UniProt
- P62937
-
