PTX3 Protein (His tag)
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- 抗原 See all PTX3 蛋白
- PTX3 (Pentraxin 3 (PTX3))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This PTX3 protein is labelled with His tag.
- 原理
- Recombinant Human PTX3/Pentraxin 3/TSG-14 Protein (His Tag)
- 序列
- Met 1-Ser 381
- 产品特性
- A DNA sequence encoding the human PTX3 (NP_002843.2) (Met 1-Ser 381) was fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 97 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product PTX3 蛋白
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Pentraxin 3 (PTX3) (AA 18-381) protein (His tag)
PTX3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % by SDS - PAGE SDS
Pentraxin 3 (PTX3) (AA 282-380) protein (GST tag)PTX3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Pentraxin 3 (PTX3) (AA 183-381) proteinPTX3 宿主: 小鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS, WB, ELISA, IP
Pentraxin 3 (PTX3) proteinPTX3 宿主: 大鼠 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS, WB, ELISA, IP
Pentraxin 3 (PTX3) protein (Myc-DYKDDDDK Tag)PTX3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- PTX3 (Pentraxin 3 (PTX3))
- 别名
- PTX3/Pentraxin 3/TSG-14 (PTX3 产品)
- 别名
- fb05a06 Protein, wu:fb05a06 Protein, TNFAIP5 Protein, TSG-14 Protein, PPTX Protein, AI607804 Protein, si:ch211-272f3.3 Protein, pentraxin 3 Protein, pentraxin related gene Protein, si:ch211-272f3.3 Protein, LOC100230343 Protein, PTX3 Protein, Ptx3 Protein
- 背景
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Background: Pentraxin-related protein PTX3, also known as Tumor necrosis factor alpha-induced protein 5, Tumor necrosis factor-inducible gene 14 protein, TSG-14, PTX3 and TNFAIP5, is a secreted protein which contains one pentaxin domain. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. Pentraxins are a family of evolutionarily conserved multifunctional pattern-recognition proteins characterized by a cyclic multimeric structure. Based on the primary structure of the subunit, the pentraxins are divided into two groups: short pentraxins and long pentraxins. C-reactive protein (CRP) and serum amyloid P-component (SAP) are the two short pentraxins. The prototype protein of the long pentraxin group is pentraxin 3 (PTX3). CRP and SAP are produced primarily in the liver in response to IL-6, while PTX3 is produced by a variety of tissues and cells and in particular by innate immunity cells in response to proinflammatory signals and Toll-like receptor (TLR) engagement. PTX3 is essential in female fertility by acting as a nodal point for the assembly of the cumulus oophorus hyaluronan-rich extracellular matrix. PTX3 interacts with several ligands, including growth factors, extracellular matrix components and selected pathogens, playing a role in complement activation and facilitating pathogen recognition by phagocytes, acting as a predecessor of antibodies. PTX3 may also contribute to the pathogenesis of atherosclerosis.
Synonym: PTX3;TNFAIP5;TSG-14
- 分子量
- 41.6 kDa
- NCBI登录号
- NP_002843
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