OPCML Protein (His tag)
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- 抗原 See all OPCML 蛋白
- OPCML (Opioid Binding Protein/cell Adhesion Molecule-Like (OPCML))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This OPCML protein is labelled with His tag.
- 原理
- Recombinant Human OBCAM/OPCML Protein (His Tag)
- 序列
- Met 1-Asn 322
- 产品特性
- A DNA sequence encoding the human OPCML precursor (NP_002536.1) (Met 1-Asn 322) was expressed with a C-terminal polyhistidine tag.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product OPCML 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- OPCML (Opioid Binding Protein/cell Adhesion Molecule-Like (OPCML))
- 别名
- OBCAM/OPCML (OPCML 产品)
- 别名
- IGLON1 Protein, OBCAM Protein, OPCM Protein, 2900075O15Rik Protein, 3732419F12 Protein, AI844366 Protein, B930023M13Rik Protein, C230027C17 Protein, Gm181 Protein, Obcam Protein, opioid binding protein/cell adhesion molecule like Protein, opioid binding protein/cell adhesion molecule-like Protein, OPCML Protein, Opcml Protein
- 背景
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Background: Opioid-binding Cell Adhesion Molecule (OBCAM), also known as OPCML, is a GPI-anchored cell adhesion molecule in the plasma membrane. This neuron-specific protein, consists of three immunoglobulin (Ig)-like domains anchored to the membrane through a glycosylphosphatidylinositol (GPI)-tail. OPCML also belongs to the member of the IgLON family, a subgroup of the immunoglobulin superfamily, consisting of three members, LAMP, OBCAM, and Neurotrimin. These molecules interact homophilically and heterophilically within the family, and OBCAM acts only as heterodimers with LAMP or Neurotrimin and possibly inhibits neurite outgrowth from cerebellar granule cells. OBCAM has been presumed to play a role as a cell adhesion/recognition molecule. Furthermore, the OPCML protein defects may play an important role in the carcinogenesis of cervical or ovarian cancers, and this gene is regarded as a candidate TSG (tumor suppressor gene).
Synonym: IGLON1,OBCAM,OPCM
- 分子量
- 34 kDa
- NCBI登录号
- NP_002536
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