NPTN Protein (His tag)
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- 抗原 See all NPTN 蛋白
- NPTN (Neuroplastin (NPTN))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This NPTN protein is labelled with His tag.
- 原理
- Recombinant Human Neuroplastin/NPTN Protein (His Tag)
- 序列
- Gln29-His220
- 产品特性
- Recombinant Human Neuroplastin is produced by our Mammalian expression system and the target gene encoding Gln29-His220 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- NPTN (Neuroplastin (NPTN))
- 别名
- Neuroplastin/NPTN (NPTN 产品)
- 别名
- SDFR1 Protein, GP55 Protein, GP65 Protein, SDR1 Protein, np55 Protein, np65 Protein, AW554172 Protein, Sdfr1 Protein, nptn Protein, zgc:77326 Protein, neuroplastin Protein, neuroplastin L homeolog Protein, neuroplastin b Protein, NPTN Protein, Nptn Protein, nptn.L Protein, nptnb Protein
- 背景
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Background: Neuroplastin (NPTN) is a 52-57 kDa member of the Ig-superfamily. Neuroplastin likely serves as a cell adhesion molecule, and is widely expressed in multiple tissues. Human Neuroplastin is 282 amino acids that contions two Ig-like domains and a 38 aa cytoplasmic region. Probable homophilic and heterophilic cell adhesion molecule involved in long term potentiation at hippocampal excitatory synapses through activation of p38MAPK. Neuroplastin may also regulate neurite outgrowth by activating the FGFR1 signaling pathway. It may play a role in synaptic plasticity.
Synonym: Neuroplastin, Stromal Cell-Derived Receptor 1, SDR-1, NPTN, SDFR1, SDR1
- 分子量
- 22.7 kDa
- UniProt
- Q9Y639
- 途径
- Regulation of long-term Neuronal Synaptic Plasticity
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