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NFASC Protein (His tag)

NFASC 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7317169
发货至: 中国
  • 抗原 See all NFASC 蛋白
    NFASC (Neurofascin (NFASC))
    蛋白类型
    Recombinant
    宿主
    资源
    • 3
    • 2
    • 1
    HEK-293 Cells
    标记
    This NFASC protein is labelled with His tag.
    原理
    Recombinant Human NFASC/Neurofascin protein (His Tag)
    序列
    Met 1-Gln939
    产品特性
    A DNA sequence encoding the human NFASC (O94856-12) (Met1-Gln939) was expressed with a C-terminal polyhistidine tag.
    纯度
    > 95 % as determined by reducing SDS-PAGE.
    内毒素水平
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product NFASC 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    NFASC (Neurofascin (NFASC))
    别名
    NFASC/Neurofascin (NFASC 产品)
    别名
    sc:d0205 Protein, NF Protein, NRCAML Protein, AA387016 Protein, D430023G06Rik Protein, mKIAA0756 Protein, neurofascin Protein, neurofascin homolog (chicken) a Protein, NFASC Protein, nfasca Protein, Nfasc Protein
    背景

    Background: NFASC, also known as neurofascin, belongs to the immunoglobulin superfamily, L1/neurofascin/NgCAM family. It contains 5 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains. NFASC functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. NFASC links the AIS extracellular matrix to the intracellular cytoskeleton.

    Synonym: NF,NRCAML

    分子量
    104.4 kDa
    途径
    Cell-Cell Junction Organization
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