MYOC Protein (His tag)
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- 抗原 See all MYOC 蛋白
- MYOC (Myocilin (MYOC))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This MYOC protein is labelled with His tag.
- 原理
- Recombinant Human MYOC/Myocilin Protein (His Tag)
- 序列
- Met 1-Met 504
- 产品特性
- A DNA sequence encoding the full length of human MYOC (Q99972) (Met 1-Met 504) was fused with a polyhistidine tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product MYOC 蛋白
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Myocilin (MYOC) (AA 36-135) protein (GST tag)
MYOC 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Myocilin (MYOC) (AA 1-504) protein (GST tag)MYOC 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Myocilin (MYOC) protein (Myc-DYKDDDDK Tag)MYOC 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- MYOC (Myocilin (MYOC))
- 别名
- MYOC/Myocilin (MYOC 产品)
- 别名
- MYOC Protein, MGC136645 Protein, zgc:136645 Protein, AI957332 Protein, GLC1A Protein, TIGR Protein, GPOA Protein, JOAG Protein, JOAG1 Protein, myocilin Protein, Tigr Protein, myocilin Protein, MYOC Protein, myoc Protein, Myoc Protein
- 背景
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Background: Myocilin, also known as Trabecular meshwork-induced glucocorticoid response protein, MYOC and GLC1A, is a protein which contains one olfactomedin-like domain. Myocilin / MYOC may participate in the obstruction of fluid outflow in the trabecular meshwork. Myocilin / MYOC is expressed in large amounts in various types of muscle, ciliary body, papillary sphincter, skeletal muscle, heart and other tissues. Myocilin / MYOC is expressed predominantly in the retina. In normal eyes, it is found in the inner uveal meshwork region and the anterior portion of the meshwork. In contrast, in many glaucomatous eyes, it is found in more regions of the meshwork and appeared more intensively than in normal eyes, regardless of the type or clinical severity of glaucoma. Defects in Myocilin / MYOC may contribute to primary congenital glaucoma type 3A (GLC3A). Defects in MYOC may also contribute to this phenotype via digenic inheritance. GLC3A is an autosomal recessive form of primary congenital glaucoma (PCG). PCG is characterized by marked increase of intraocular pressure at birth or early choldhood, large ocular globes (buphthalmos) and corneal edema.
Synonym: GLC1A;GPOA;JOAG;JOAG1;myocilin;TIGR
- 分子量
- 54.7 kDa
- UniProt
- Q99972
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