MPZL1 Protein (His tag)
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- 抗原 See all MPZL1 蛋白
- MPZL1 (Myelin Protein Zero-Like 1 (MPZL1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 人细胞
- 标记
- This MPZL1 protein is labelled with His tag.
- 原理
- Recombinant Human MPZL1 Protein (His Tag)
- 序列
- Ser36-Val162
- 产品特性
- Recombinant Human Myelin Protein P0-like 1 is produced by our Mammalian expression system and the target gene encoding Ser36-Val162 is expressed with a 6His tag at the C-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product MPZL1 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- MPZL1 (Myelin Protein Zero-Like 1 (MPZL1))
- 别名
- MPZL1 (MPZL1 产品)
- 别名
- MPZL1 Protein, MPZL1b Protein, PZR Protein, PZR1b Protein, PZRa Protein, PZRb Protein, 1110007A10Rik Protein, myelin protein zero like 1 Protein, myelin protein zero-like 1 Protein, MPZL1 Protein, Mpzl1 Protein
- 背景
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Background: Myelin protein zero-like protein 1(MPZL1) is encoded by the MPZL1 gene, which is a single-pass type I membrane protein. It is widely expressed with highest levels in heart, placenta, kidney and pancreas. As cell surface receptor, it involved in signal transduction processes. MPZL1 recruits PTPN11/SHP-2 to the cell membrane and subsequently activate/phosphorylate Src kinase at Tyr426, promoting phosphorylation of cortactin and migration of HCC cells. MPZL1also is a major receptor for concanavalin-A (ConA) and involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases.
Synonym: Myelin protein zero-like 1, isoform CRA_b,cDNA FLJ78597, highly similar to Homo sapiens myelin protein zero-like 1 (MPZL1), transcript variant 1, mRNA ,cDNA, FLJ96614, Homo sapiens myelin protein zero-like 1 (MPZL1), Mrna
- 分子量
- 15.2 kDa
- UniProt
- O95297
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