MME 蛋白
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- 抗原 See all MME 蛋白
- MME (Membrane Metallo-Endopeptidase (MME))
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- 人
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资源
- HEK-293 Cells
- 原理
- Recombinant Human CD10/Neprilysin Protein (Active)
- 序列
- Tyr 52-Trp 750
- 产品特性
- A DNA sequence encoding the extracellular domain (Tyr 52-Trp 750) of human MME (NP_000893.2) was expressed and purified.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Measured by its ability to cleave the fluorogenic peptide substrate, Mca-RPPGFSAFK(Dnp)-OH, (R&D Systems, Catalog # ES005). The specific activity is >1,000 pmoles/min/μg.
- Top Product
- Discover our top product MME 蛋白
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Membrane Metallo-Endopeptidase (MME) (AA 52-750) protein (His tag)
MME 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Membrane Metallo-Endopeptidase (MME) (AA 52-750) protein (His tag)MME 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Membrane Metallo-Endopeptidase (MME) (AA 53-750) protein (His tag)MME 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Membrane Metallo-Endopeptidase (MME) (AA 1-750) protein (GST tag)MME 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Membrane Metallo-Endopeptidase (MME) (AA 52-750) protein (His tag)MME 宿主: 人 宿主: Baculovirus infected Insect Cells Recombinant > 95 % by SDS - PAGE SDS
Membrane Metallo-Endopeptidase (MME) protein (Fc Tag)MME 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Membrane Metallo-Endopeptidase (MME) protein (His tag)MME 宿主: 大鼠 宿主: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- MME (Membrane Metallo-Endopeptidase (MME))
- 别名
- CD10/Neprilysin (MME 产品)
- 背景
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Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 10 (CD10), also known as Neprilysin and neutral endopeptidase, is a member of the CD system. CD10 is a zinc-dependent metalloprotease enzyme that had function to degrade a number of small secreted peptides such as the amyloid beta peptide. It exist as a membrane-bound protein and have high concentration in kidney and lung tissues. Mutations in the CD10 gene can induce the familial forms of Alzheimer's disease, providing strong evidence for the protein's association with the Alzheimer's disease process. CD10 is also associated with other biochemical processes.
Synonym: CALLA,CD10,NEP,SFE
- 分子量
- 80 kDa
- NCBI登录号
- NP_000893
- 途径
- RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration
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