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MMP8 蛋白

MMP8 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 85 % as determined by SDS-PAGE
产品编号 ABIN7320257
发货至: 中国
  • 抗原 See all MMP8 蛋白
    MMP8 (Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8))
    蛋白类型
    Recombinant
    宿主
    • 9
    • 4
    • 3
    • 2
    • 1
    小鼠
    资源
    • 10
    • 6
    • 1
    • 1
    HEK-293 Cells
    原理
    Recombinant Mouse MMP8/CLG1 Protein
    序列
    Phe 21-Ser 465
    产品特性
    A DNA sequence encoding the pro form of mouse MMP8 (NP_032637.3) (Phe 21-Ser 465) was expressed and purified, with an initial Met at the N-terminus.
    纯度
    > 85 % as determined by SDS-PAGE
    内毒素水平
    < 1.0 EU per μg of the protein as determined by the LAL method.
    Top Product
    Discover our top product MMP8 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    MMP8 (Matrix Metallopeptidase 8 (Neutrophil Collagenase) (MMP8))
    别名
    MMP8/CLG1 (MMP8 产品)
    别名
    MMP8 Protein, BB138268 Protein, CLG1 Protein, HNC Protein, MMP-8 Protein, PMNL-CL Protein, matrix metallopeptidase 8 Protein, neutrophil collagenase Protein, MMP8 Protein, Mmp8 Protein, LOC100339790 Protein
    背景

    Background: Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases and tumor invasion. Neutrophil collagenase, also known as Matrix metalloproteinase-8, MMP-8, and CLG1, is a member of the peptidase M10A family. MMP-8 may affect the metastatic behaviour of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in drug development. MMP-8 in the tumour may have a protective effect against lymph node metastasis. MMP-8 may affect the metastatic behaviour of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in drug development. MMP-8 participates in wound repair by contributing to the resolution of inflammation and open the possibility to develop new strategies for treating wound healing defects.

    Synonym: BB138268

    分子量
    52 kDa
    NCBI登录号
    NP_032637
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