MBIP Protein (His tag)
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- 抗原 See all MBIP 蛋白
- MBIP (MAP3K12-Binding Inhibitory Protein 1 (MBIP))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 标记
- This MBIP protein is labelled with His tag.
- 原理
- Recombinant Human MBIP Protein (His Tag)
- 序列
- Met 1-Pro344
- 产品特性
- Recombinant Human MAP3K12-Binding Inhibitory Protein 1 is produced by our E.coli expression system and the target gene encoding Met1-Pro344 is expressed with a 6His tag at the N-terminus.
- 纯度
- > 95 % as determined by reducing SDS-PAGE.
- 内毒素水平
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product MBIP 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Please refer to the printed manual for detailed information.
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, pH 8.0.
- 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- 抗原
- MBIP (MAP3K12-Binding Inhibitory Protein 1 (MBIP))
- 别名
- MBIP (MBIP 产品)
- 别名
- 4933408E06Rik Protein, MAP3K12 binding inhibitory protein 1 Protein, Mbip Protein, mbip Protein, MBIP Protein
- 背景
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Background: MAP3K12-binding inhibitory protein 1 (MBIP) is a 39kD protein high expression in the heart and lung. It is a component of the ADA2A-containing complex (ATAC) complex, a complex with histone acetyltransferase activity on histones H3 and H4, and composed of CSRP2BP, KAT2A, TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1. In the complex, it probably interacts directly with KAT2A, CSRP2BP and WDR5. It's function to inhibit the MAP3K12 activity to induce the activation of the JNK/SAPK pathway.
Synonym: MAP3K12-Binding Inhibitory Protein 1, MAPK Upstream Kinase-Binding Inhibitory Protein, MUK-Binding Inhibitory Protein, MBIP
- 分子量
- 42.5 kDa
- UniProt
- Q9NS73
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