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LAIR2 蛋白

LAIR2 宿主: 人 宿主: HEK-293 Cells Recombinant > 94 % as determined by reducing SDS-PAGE.
产品编号 ABIN7196816
发货至: 中国
  • 抗原 See all LAIR2 蛋白
    LAIR2 (Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2))
    蛋白类型
    Recombinant
    宿主
    资源
    • 7
    • 2
    • 1
    • 1
    HEK-293 Cells
    原理
    Recombinant Human LAIR2/CD306 Protein, Low Endotoxin
    序列
    Met 1-Pro 152
    产品特性
    A DNA sequence encoding the human LAIR2 (NP_002279.2) (Met 1-Pro 152) was expressed and purified.
    纯度
    > 94 % as determined by reducing SDS-PAGE.
    内毒素水平
    5 EU per 1 mg protein as determined by the LAL method. Frozen shipping is required
    Top Product
    Discover our top product LAIR2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Please refer to the printed manual for detailed information.
    缓冲液
    Lyophilized from sterile PBS, pH 7.4
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • 抗原
    LAIR2 (Leukocyte-Associated Immunoglobulin-Like Receptor 2 (LAIR2))
    别名
    LAIR2/CD306 (LAIR2 产品)
    别名
    CD306 Protein, leukocyte associated immunoglobulin like receptor 2 Protein, LAIR2 Protein
    背景

    Background: Leukocyte-associated immunoglobulin-like receptor 2 ( LAIR2 ), also known as CD306, is a 131 amino acid protein containing one lg-like C2-type domain. It is expressed as a soluble receptor exhibiting high affinity for various collagen molecules to which it binds in a hydroxyproline-dependent manner. LAIR2 is a member of the immunoglobulin superfamily and was identified by its similarity to LAIR1, an inhibitory receptor present on mononuclear leukocytes. LAIR2 is thought to be secreted and may help modulate mucosal tolerance. As a natural competitor for LAIR1, soluble LAIR2 prevents binding of human LAIR1 to collagens and LAIR1 cross-linking, thereby regulating its inhibitory potential. Accordingly, LAIR2 is suggested to perform an immunoregulatory function.

    Synonym: CD306,LAIR2,MGC71634,XXbac-BCX535A19.6

    分子量
    14.1 kDa
    NCBI登录号
    NP_002279
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